Advancing Biomedical Frontiers with Functionalized Soybean Oil: Insights into Tissue Engineering and Drug Delivery

IF 4.7 3区 工程技术 Q2 ENGINEERING, ENVIRONMENTAL Journal of Polymers and the Environment Pub Date : 2024-07-30 DOI:10.1007/s10924-024-03357-8
Vafa Fakhri, Atieh Janmaleki Dehchani, Seyed Aref Davoudi, Masoud Tavakoli Dare, Aliakbar Jafari, Saba Nemati Mahand, Elmuez A. Dawi, Hossein Ali Khonakdar
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Abstract

Soybean oil is one of the most widely produced and consumed vegetable oils globally. Known for its rich fatty acid composition, including linoleic, oleic, and alpha-linolenic acids, soybean oil offers substantial nutritional and health benefits. It is not only a dietary staple but also a versatile component in industrial and biomedical applications. This review paper offers a comprehensive discussion on the emerging role of functionalized soybean oil (SO) in the development of sustainable polymers for tissue engineering (TE) and drug delivery systems (DDS). Plant oils, particularly soybean oil, offer significant environmental benefits, making them an excellent substitute for petroleum-based polymers and biomedical applications due to their biodegradability and low ecological footprint. Despite the burgeoning potential of soybean oil-derived polymers in revolutionizing natural-based biomaterials, there is a critical need for an in-depth review to thoroughly comprehend their capabilities and steer forthcoming innovations.This review aims to address the scientific gap by offering a comprehensive analysis of recent advancements in the biomedical application of soybean oil derivatives. The impact of this paper lies in its systematic collation of research on the design, fabrication, and utility of soybean oil-derived biomaterials, highlighting their significance in various medical applications, including therapeutic patches, wound care, and scaffolding in regenerative medicine. The review suggests future research directions and sets the stage for future innovations in soybean oil-based biomaterials, positioning these materials as crucial components in the pursuit of sustainable and effective biomedical solutions.

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利用功能化大豆油推进生物医学前沿:组织工程和药物输送的启示
大豆油是全球生产和消费最广泛的植物油之一。大豆油以其丰富的脂肪酸组成(包括亚油酸、油酸和α-亚麻酸)而闻名,具有巨大的营养和健康益处。它不仅是一种主食,也是工业和生物医学应用中的一种多功能成分。本综述论文全面探讨了功能化大豆油 (SO) 在开发用于组织工程 (TE) 和药物输送系统 (DDS) 的可持续聚合物中的新兴作用。植物油,尤其是大豆油,具有显著的环境效益,由于其生物降解性和低生态足迹,使其成为石油基聚合物和生物医学应用的绝佳替代品。尽管大豆油衍生聚合物在革新天然生物材料方面潜力巨大,但我们仍迫切需要对其进行深入研究,以全面了解其性能并引导即将到来的创新。本综述旨在通过全面分析大豆油衍生物在生物医学应用方面的最新进展来弥补这一科学空白。本文的影响力在于系统整理了有关大豆油衍生生物材料的设计、制造和实用性的研究,强调了它们在各种医疗应用中的重要意义,包括治疗贴片、伤口护理和再生医学中的支架。该综述提出了未来的研究方向,并为大豆油基生物材料的未来创新奠定了基础,将这些材料定位为追求可持续和有效生物医学解决方案的重要组成部分。
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来源期刊
Journal of Polymers and the Environment
Journal of Polymers and the Environment 工程技术-高分子科学
CiteScore
9.50
自引率
7.50%
发文量
297
审稿时长
9 months
期刊介绍: The Journal of Polymers and the Environment fills the need for an international forum in this diverse and rapidly expanding field. The journal serves a crucial role for the publication of information from a wide range of disciplines and is a central outlet for the publication of high-quality peer-reviewed original papers, review articles and short communications. The journal is intentionally interdisciplinary in regard to contributions and covers the following subjects - polymers, environmentally degradable polymers, and degradation pathways: biological, photochemical, oxidative and hydrolytic; new environmental materials: derived by chemical and biosynthetic routes; environmental blends and composites; developments in processing and reactive processing of environmental polymers; characterization of environmental materials: mechanical, physical, thermal, rheological, morphological, and others; recyclable polymers and plastics recycling environmental testing: in-laboratory simulations, outdoor exposures, and standardization of methodologies; environmental fate: end products and intermediates of biodegradation; microbiology and enzymology of polymer biodegradation; solid-waste management and public legislation specific to environmental polymers; and other related topics.
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