Progress Toward the Elimination of Hepatitis B and Hepatitis C in the Country of Georgia, April 2015-April 2024.

IF 25.4 1区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH MMWR. Morbidity and mortality weekly report Pub Date : 2024-08-01 DOI:10.15585/mmwr.mm7330a1
Rania A Tohme, Shaun Shadaker, Ekaterine Adamia, Irma Khonelidze, Ketevan Stvilia, Vladimer Getia, Maia Tsereteli, Maia Alkhazashvili, Akaki Abutidze, Maia Butsashvili, Maka Gogia, Nancy Glass, Sophia Surguladze, Irina Tskhomelidze Schumacher, Tamar Gabunia
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Abstract

Hepatitis B and hepatitis C are leading causes of cirrhosis and liver cancer and caused 1.3 million deaths worldwide in 2022. Hepatitis B is preventable with vaccination, and hepatitis C is curable with direct-acting antivirals. In 2015, in collaboration with CDC and other partners, Georgia, a country at the intersection of Europe and Asia, launched a hepatitis C elimination program to reduce the prevalence of chronic hepatitis C; at that time, the prevalence was 5.4%, more than five times the global average of 1.0%. In 2016, the World Health Assembly endorsed a goal for the elimination of viral hepatitis as a public health problem by 2030. In 2024, 89% of the Georgian adult population have received screening for hepatitis C, 83% of persons with current chronic HCV infection have received a diagnosis, and 86% of those with diagnosed hepatitis C have started treatment. During 2015-2023, vaccination coverage with the hepatitis B birth dose and with 3 doses of hepatitis B vaccine among infants exceeded 90% for most years. In 2021, the prevalence of hepatitis B surface antigen was 0.03% among children and adolescents aged 5-17 years and 2.7% among adults. Georgia has demonstrated substantial progress toward hepatitis B and hepatitis C elimination. Using lessons from the hepatitis C elimination program, scale-up of screening and treatment for hepatitis B among adults would prevent further viral hepatitis-associated morbidity and mortality in Georgia and would accelerate progress toward hepatitis B and hepatitis C elimination by 2030.

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2015 年 4 月至 2024 年 4 月格鲁吉亚消除乙型肝炎和丙型肝炎的进展情况。
乙型肝炎和丙型肝炎是导致肝硬化和肝癌的主要原因,2022 年将导致全球 130 万人死亡。乙型肝炎可通过接种疫苗预防,丙型肝炎可通过直接作用抗病毒药物治愈。2015 年,位于欧亚交界处的格鲁吉亚与美国疾病预防控制中心和其他合作伙伴合作,启动了一项消除丙型肝炎计划,以降低慢性丙型肝炎的流行率;当时的流行率为 5.4%,是全球平均流行率 1.0% 的五倍多。2016 年,世界卫生大会批准了到 2030 年消除病毒性肝炎这一公共卫生问题的目标。2024 年,89% 的格鲁吉亚成年人接受了丙型肝炎筛查,83% 的当前慢性丙型肝炎病毒感染者得到了诊断,86% 的确诊丙型肝炎患者开始了治疗。2015-2023 年期间,婴儿出生时接种乙肝疫苗和接种 3 剂乙肝疫苗的覆盖率在大多数年份都超过了 90%。2021 年,乙型肝炎表面抗原在 5-17 岁儿童和青少年中的流行率为 0.03%,在成年人中的流行率为 2.7%。格鲁吉亚在消除乙型肝炎和丙型肝炎方面取得了实质性进展。借鉴消除丙型肝炎计划的经验,在成年人中扩大乙型肝炎筛查和治疗的规模将防止格鲁吉亚进一步发生与病毒性肝炎相关的发病率和死亡率,并将加快到 2030 年消除乙型肝炎和丙型肝炎的步伐。
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来源期刊
MMWR. Morbidity and mortality weekly report
MMWR. Morbidity and mortality weekly report PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH -
CiteScore
65.40
自引率
0.90%
发文量
309
期刊介绍: The Morbidity and Mortality Weekly Report (MMWR ) series is prepared by the Centers for Disease Control and Prevention (CDC). Often called “the voice of CDC,” the MMWR series is the agency’s primary vehicle for scientific publication of timely, reliable, authoritative, accurate, objective, and useful public health information and recommendations. MMWR readership predominantly consists of physicians, nurses, public health practitioners, epidemiologists and other scientists, researchers, educators, and laboratorians.
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