Carbon quantum dots for the diagnosis and treatment of ophthalmic diseases.

IF 4.3 3区 材料科学 Q1 ENGINEERING, ELECTRICAL & ELECTRONIC ACS Applied Electronic Materials Pub Date : 2024-09-01 Epub Date: 2024-08-02 DOI:10.1007/s13577-024-01111-9
Xi Zhang, Liang Yang, Feng Wang, Ying Su
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Abstract

Carbon quantum dots (CQDs), an emerging nanomaterial, are gaining attention in ophthalmological applications due to their distinctive physical, chemical, and biological characteristics. For example, their inherent fluorescent capabilities offer a novel and promising alternative to conventional fluorescent dyes for ocular disease diagnostics. Furthermore, because of the excellent biocompatibility and minimal cytotoxicity, CQDs are well-suited for therapeutic applications. In addition, functionalized CQDs can effectively deliver drugs to the posterior part of the eyeball to inhibit neovascularization. This review details the use of CQDs in the management of ophthalmic diseases, including various retinal diseases, and ocular infections. While still in its initial phases within ophthalmology, the significant potential of CQDs for diagnosing and treating eye conditions is evident.

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用于诊断和治疗眼科疾病的碳量子点。
碳量子点(CQDs)是一种新兴的纳米材料,由于其独特的物理、化学和生物特性,其在眼科领域的应用正日益受到关注。例如,碳量子点固有的荧光功能为眼科疾病诊断提供了传统荧光染料的新颖替代品,前景广阔。此外,由于 CQD 具有出色的生物相容性和极低的细胞毒性,因此非常适合用于治疗。此外,功能化 CQDs 还能有效地将药物输送到眼球后部,抑制新生血管。本综述详细介绍了 CQDs 在眼科疾病(包括各种视网膜疾病和眼部感染)治疗中的应用。虽然 CQDs 在眼科领域仍处于初始阶段,但其在诊断和治疗眼部疾病方面的巨大潜力是显而易见的。
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来源期刊
CiteScore
7.20
自引率
4.30%
发文量
567
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