Carlos Julian Diaz-Torres, Ricardo Abanto Hinostroza
{"title":"[Solitary splenic neoplasm as an unusual presentation in an adolescent with sporadic Burkitt lymphoma].","authors":"Carlos Julian Diaz-Torres, Ricardo Abanto Hinostroza","doi":"10.32641/andespediatr.v95i3.4824","DOIUrl":null,"url":null,"abstract":"<p><p>Burkitt lymphoma is a non-Hodgkin B-cell lymphoma with a high prevalence in the pediatric population. Abdominal manifestations are well known in sporadic Burkitt lymphoma and vary from nonspecific symptoms to intestinal obstruction due to intussusception; however, mass-like splenic involvement has been scarcely described.</p><p><strong>Objective: </strong>To present a case of a patient with a splenic mass whose histopathological analysis revealed Burkitt lymphoma.</p><p><strong>Clinical case: </strong>A 13-year-old female patient presented with abdominal pain, progressive weight loss, and fever. Imaging studies showed a splenic mass, intestinal thickening, and ileal intussusception. Histopathological analysis of spleen biopsy revealed Burkitt lymphoma. After the first cycle of chemotherapy (BFM95-NHL protocol), abdominal symptoms resolved; no other signs suggestive of intussusception were observed, as well as a significant reduction of the splenic mass was observed.</p><p><strong>Conclusions: </strong>Burkitt lymphoma in pediatric patients can present as a well-defined splenic tumor, causing no splenomegaly. In addition, its management does not require surgery since it can be resolved with chemotherapy.</p>","PeriodicalId":72196,"journal":{"name":"Andes pediatrica : revista Chilena de pediatria","volume":"95 3","pages":"297-302"},"PeriodicalIF":0.5000,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Andes pediatrica : revista Chilena de pediatria","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.32641/andespediatr.v95i3.4824","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/4/14 0:00:00","PubModel":"Epub","JCR":"Q4","JCRName":"PEDIATRICS","Score":null,"Total":0}
引用次数: 0
Abstract
Burkitt lymphoma is a non-Hodgkin B-cell lymphoma with a high prevalence in the pediatric population. Abdominal manifestations are well known in sporadic Burkitt lymphoma and vary from nonspecific symptoms to intestinal obstruction due to intussusception; however, mass-like splenic involvement has been scarcely described.
Objective: To present a case of a patient with a splenic mass whose histopathological analysis revealed Burkitt lymphoma.
Clinical case: A 13-year-old female patient presented with abdominal pain, progressive weight loss, and fever. Imaging studies showed a splenic mass, intestinal thickening, and ileal intussusception. Histopathological analysis of spleen biopsy revealed Burkitt lymphoma. After the first cycle of chemotherapy (BFM95-NHL protocol), abdominal symptoms resolved; no other signs suggestive of intussusception were observed, as well as a significant reduction of the splenic mass was observed.
Conclusions: Burkitt lymphoma in pediatric patients can present as a well-defined splenic tumor, causing no splenomegaly. In addition, its management does not require surgery since it can be resolved with chemotherapy.