Innovative Biosensor Technologies in the Diagnosis of Urinary Tract Infections: A Comprehensive Literature Review

IF 2.1 4区 生物学 Q3 BIOTECHNOLOGY & APPLIED MICROBIOLOGY Indian Journal of Microbiology Pub Date : 2024-08-02 DOI:10.1007/s12088-024-01359-7
Haluk Çelik, Balım Bengisu Caf, Gizem Çebi
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Abstract

Urinary tract infections (UTIs) are prevalent bacterial infections globally, posing significant challenges due to their frequency, recurrence, and antibiotic resistance. This review delves into the advancements in UTI diagnostics over the past decade, particularly focusing on the development of biosensor technologies. The emergence of biosensors, including microfluidic, optical, electrochemical, immunosensors, and nanotechnology-based sensors, offers enhanced diagnostic accuracy, reduced healthcare costs. Despite these advancements, challenges such as technical limitations, the need for cross-population validation, and economic barriers for widespread implementation persist. The integration of artificial intelligence and smart devices in UTI diagnostics, highlighting the innovative approaches and their implications for patient care. The article envisions a future where multidisciplinary research and innovation overcome current obstacles, fully leveraging the potential of biosensor technologies to transform biosensor-based UTIs diagnosis. The ultimate goal is to achieve rapid, accurate, and non-invasive diagnostics, making healthcare more accessible and effective.

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创新生物传感器技术在尿路感染诊断中的应用:综合文献综述
尿路感染(UTI)是全球普遍存在的细菌感染,由于其发病率、复发率和抗生素耐药性,给人们带来了巨大的挑战。本综述深入探讨了过去十年UTI 诊断技术的发展,尤其关注生物传感器技术的发展。生物传感器(包括微流控、光学、电化学、免疫传感器和基于纳米技术的传感器)的出现提高了诊断的准确性,降低了医疗成本。尽管取得了这些进步,但技术限制、跨人群验证需求和广泛应用的经济障碍等挑战依然存在。人工智能和智能设备在UTI诊断中的整合,突出了创新方法及其对患者护理的影响。文章设想,未来多学科研究和创新将克服当前的障碍,充分利用生物传感器技术的潜力,改变基于生物传感器的 UTI 诊断。最终目标是实现快速、准确和无创诊断,使医疗保健更加方便有效。
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来源期刊
Indian Journal of Microbiology
Indian Journal of Microbiology BIOTECHNOLOGY & APPLIED MICROBIOLOGY-MICROBIOLOGY
CiteScore
6.00
自引率
10.00%
发文量
51
审稿时长
1 months
期刊介绍: Indian Journal of Microbiology is the official organ of the Association of Microbiologists of India (AMI). It publishes full-length papers, short communication reviews and mini reviews on all aspects of microbiological research, published quarterly (March, June, September and December). Areas of special interest include agricultural, food, environmental, industrial, medical, pharmaceutical, veterinary and molecular microbiology.
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