Dharti R. Bhandari , Urvi J. Khengar , Rajesh H. Vekariya , Jinal A. Gajjar
{"title":"Recent advances in meglumine catalyzed organic synthesis: A comprehensive review","authors":"Dharti R. Bhandari , Urvi J. Khengar , Rajesh H. Vekariya , Jinal A. Gajjar","doi":"10.1080/00397911.2024.2380062","DOIUrl":null,"url":null,"abstract":"<div><p>Meglumine, an amino sugar alcohol compound, has recently emerged as a promising catalyst in various organic transformations due to its unique properties. This review provides a comprehensive overview of the applications of meglumine catalyst in organic synthesis, highlighting their efficiency, versatility, and mechanistic insights. Key examples of reactions catalyzed by meglumine, including aldol condensation, Michael addition, Mannich reaction, and other one-pot multicomponent condensation reaction are discussed along with mechanistic pathways and synthetic strategies. Additionally, recent advancements and future perspectives in the field are explored.</p></div>","PeriodicalId":22119,"journal":{"name":"Synthetic Communications","volume":"54 16","pages":"Pages 1285-1310"},"PeriodicalIF":1.8000,"publicationDate":"2024-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Synthetic Communications","FirstCategoryId":"92","ListUrlMain":"https://www.sciencedirect.com/org/science/article/pii/S0039791124000730","RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CHEMISTRY, ORGANIC","Score":null,"Total":0}
引用次数: 0
Abstract
Meglumine, an amino sugar alcohol compound, has recently emerged as a promising catalyst in various organic transformations due to its unique properties. This review provides a comprehensive overview of the applications of meglumine catalyst in organic synthesis, highlighting their efficiency, versatility, and mechanistic insights. Key examples of reactions catalyzed by meglumine, including aldol condensation, Michael addition, Mannich reaction, and other one-pot multicomponent condensation reaction are discussed along with mechanistic pathways and synthetic strategies. Additionally, recent advancements and future perspectives in the field are explored.
期刊介绍：
Synthetic Communications presents communications describing new methods, reagents, and other synthetic work pertaining to organic chemistry with sufficient experimental detail to permit reported reactions to be repeated by a chemist reasonably skilled in the art. In addition, the Journal features short, focused review articles discussing topics within its remit of synthetic organic chemistry.
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