Brief communication: reasons for non-adherence of co-trimoxazole prophylaxis therapy among people living with HIV in a resource-limited setting, Northern Ethiopia.

IF 2.1 4区 医学 Q3 INFECTIOUS DISEASES AIDS Research and Therapy Pub Date : 2024-08-05 DOI:10.1186/s12981-024-00635-2
Gebrehiwot Teklay, Meryem Mohammedbrhan, Desilu Mahari Desta
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Abstract

This study aimed to assess the prevalence and reasons for nonadherence to cotrimoxazole prophylaxis therapy. A cross-sectional study was conducted among people living with HIV attending Ayder Comprehensive Specialized Hospital. Data were collected through interviews and reviews of medical records. Binary logistic regression was employed to analyze factors associated with CPT nonadherence. Approximately two-thirds (65.5%) of the participants were non-adherent to co-trimoxazole prophylaxis therapy. The main reasons for non-adherence were side effects, pill fatigue and forgetfulness. Strategies to improve adherence to co-trimoxazole prophylaxis therapy should focus on the combined patient, clinical and medication related issues of people living with HIV.

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简讯:埃塞俄比亚北部一个资源有限地区的艾滋病毒感染者不坚持联合三唑预防疗法的原因。
本研究旨在评估不坚持复方新诺明预防治疗的流行率和原因。研究对艾德综合专科医院的艾滋病毒感染者进行了横断面调查。数据是通过访谈和查阅病历收集的。采用二元逻辑回归分析与不坚持 CPT 相关的因素。约有三分之二(65.5%)的参与者未坚持接受联合三唑预防疗法。不坚持治疗的主要原因是副作用、服药疲劳和健忘。改善联合曲唑预防疗法依从性的策略应关注艾滋病病毒感染者的患者、临床和药物相关问题。
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来源期刊
AIDS Research and Therapy
AIDS Research and Therapy INFECTIOUS DISEASES-
CiteScore
3.80
自引率
4.50%
发文量
51
审稿时长
16 weeks
期刊介绍: AIDS Research and Therapy publishes articles on basic science, translational, clinical, social, epidemiological, behavioral and educational sciences articles focused on the treatment and prevention of HIV/AIDS, and the search for the cure. The Journal publishes articles on novel and developing treatment strategies for AIDS as well as on the outcomes of established treatment strategies. Original research articles on animal models that form an essential part of the AIDS treatment research are also considered
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