Evaluating VATS versus Open Surgery for Non-Small Cell Lung Cancer: A 5-year Retrospective Study.

IF 0.8 Q4 SURGERY Chirurgia Pub Date : 2024-08-01 DOI:10.21614/chirurgia.2999
Alin Ionut Burlacu, Bogdan Cosmin Tanase, Iolanda Augustin, Gabriel Veniamin Cozma
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Abstract

Background and objectives: The efficacy and safety of video-assisted thoracoscopic surgery (VATS) versus open thoracotomy in the treatment of non-small cell lung cancer (NSCLC) were evaluated with a focus on mediastinal lymph node dissection, postoperative recovery, and longterm outcomes including survival rates and disease-free intervals. Materials and Methods: This retrospective study analyzed data from 228 NSCLC patients treated at the Institute of Oncology Bucharest from 2016 to 2022. Both VATS and open surgical approaches were compared, with variables including demographic data, comorbidities, surgical outcomes, and postoperative complications meticulously recorded. Statistical significance was assessed using chi-square and independent samples t-tests. Results: Among the findings, VATS demonstrated significantly better two-year progression-free survival rates for patients in early stages (Stages 1-3) of NSCLC compared to open surgery, with p-values 0.01 and 0.001, respectively. In contrast, no significant difference was observed in Stage 4. Furthermore, VATS resulted in shorter operative times (mean 299 vs. 347 minutes, p 0.001), less estimated blood loss (98.68 mL vs. 160.88 mL, p 0.001), reduced chest tube duration (5.78 days vs. 12.17 days, p 0.001), and decreased hospital stays (12.0 days vs. 27.7 days, p 0.001). Conclusions: VATS is associated with improved long-term disease-free survival for early-stage NSCLC and more favorable short-term surgical outcomes, highlighting its advantages over open thoracotomy. Despite its benefits, VATS did not significantly reduce postoperative complications compared to open surgery.

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评估非小细胞肺癌 VATS 与开放手术:五年回顾性研究
背景和目的:评估视频辅助胸腔镜手术(VATS)与开胸手术治疗非小细胞肺癌(NSCLC)的疗效和安全性,重点关注纵隔淋巴结清扫、术后恢复以及包括生存率和无病间隔期在内的长期疗效。材料和方法:这项回顾性研究分析了布加勒斯特肿瘤研究所从2016年至2022年治疗的228名NSCLC患者的数据。比较了 VATS 和开放手术两种方法,并详细记录了人口统计学数据、合并症、手术结果和术后并发症等变量。统计意义采用卡方检验和独立样本 t 检验进行评估。结果研究结果表明,与开放手术相比,VATS 手术对早期(1-3 期)NSCLC 患者的两年无进展生存率明显更高,P 值分别为 0.01 和 0.001。相比之下,第 4 期患者则无明显差异。此外,VATS 手术时间更短(平均 299 分钟对 347 分钟,P 0.001),估计失血量更少(98.68 毫升对 160.88 毫升,P 0.001),胸管插管时间更短(5.78 天对 12.17 天,P 0.001),住院时间更短(12.0 天对 27.7 天,P 0.001)。结论:与开胸手术相比,VATS 可提高早期 NSCLC 的长期无病生存率,并获得更有利的短期手术效果,这凸显了它的优势。与开胸手术相比,VATS 尽管有其优势,但并不能显著减少术后并发症。
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来源期刊
Chirurgia
Chirurgia Medicine-Surgery
CiteScore
1.00
自引率
0.00%
发文量
75
审稿时长
4-8 weeks
期刊介绍: Chirurgia is a bimonthly journal. In Chirurgia, original papers in the area of general surgery which neither appeared, nor were sent for publication in other periodicals, can be published. You can send original articles, new surgical techniques, or comprehensive general reports on surgical topics, clinical case presentations and, depending on publication space, - reviews of some articles of general interest to surgeons from other publications. Chirurgia is also a place for sharing information about the activity of various branches of the Romanian Society of Surgery, information on Congresses and Symposiums organized by the Romanian Society of Surgery and participation notes in other scientific meetings. Letters to the editor: Letters commenting on papers published in Chirurgia are welcomed. They should contain substantive ideas and commentaries supported by appropriate data, and should not exceed 2 pages. Please submit these letters to the editor through our online system.
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