A View in the Dark: Two Cases of Acute Esophageal Necrosis in the Setting of Diabetic Ketoacidosis.

IF 0.9 Q3 MEDICINE, GENERAL & INTERNAL Journal of investigative medicine high impact case reports Pub Date : 2024-01-01 DOI:10.1177/23247096241269864
Lefika Bathobakae, Rammy Bashir, Dhruv Patel, Tyler Wilkinson, Nader Mekheal, Gabriel Melki, Yana Cavanagh, Walid Baddoura
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Abstract

Acute esophageal necrosis (AEN), also known as Gurvits syndrome, is a rare and potentially life-threatening condition characterized by necrosis of the esophageal mucosa. Acute esophageal necrosis is often associated with critical conditions, such as myocardial infarction, diabetic ketoacidosis (DKA), coronavirus disease 2019 (COVID-19) infection, or post-surgical complications. Patients typically present with nausea, hematemesis, acute dysphagia, and melena. Given its high mortality rate, prompt detection with upper endoscopy and early initiation of treatment are crucial. Most cases of Gurvits syndrome are managed conservatively using intravenous fluids, proton pump inhibitors, and antibiotics. Herein, we present a case series of AEN in the setting of DKA. Both patients received supportive care and were discharged in a stable condition.

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黑暗中的视角:两例糖尿病酮症酸中毒急性食管坏死病例。
急性食管坏死(AEN)又称古尔维茨综合征,是一种以食管粘膜坏死为特征的罕见且可能危及生命的疾病。急性食管坏死通常与心肌梗塞、糖尿病酮症酸中毒(DKA)、2019 年冠状病毒病(COVID-19)感染或手术后并发症等危重情况有关。患者通常表现为恶心、吐血、急性吞咽困难和腹泻。鉴于该病的高死亡率,通过上内镜及时发现并尽早开始治疗至关重要。大多数古尔维茨综合征病例可通过静脉输液、质子泵抑制剂和抗生素进行保守治疗。在此,我们介绍一例在发生 DKA 时出现 AEN 的系列病例。两名患者均接受了支持性治疗,病情稳定后出院。
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来源期刊
CiteScore
1.90
自引率
0.00%
发文量
165
审稿时长
12 weeks
期刊介绍: The AFMR is committed to enhancing the training and career development of our members and to furthering its mission to facilitate the conduct of research to improve medical care. Case reports represent an important avenue for trainees (interns, residents, and fellows) and early-stage faculty to demonstrate productive, scholarly activity.
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