Risk Factors for Recurrent Proximal Junctional Failure Following Adult Spinal Deformity Surgery: Analysis of 60 Patients Undergoing Fusion Extension Surgery for Proximal Junctional Failure.

IF 1.7 Q2 SURGERY International Journal of Spine Surgery Pub Date : 2024-08-06 DOI:10.14444/8620
Se-Jun Park, Jin-Sung Park, Dong-Ho Kang, Chong-Suh Lee, Hyun-Jun Kim
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Abstract

Background: Despite numerous studies identifying risk factors for proximal junctional failure (PJF), risk factors for recurrent PJF (R-PJF) are still not well established. Therefore, we aimed to identify the risk factors for R-PJF following adult spinal deformity (ASD) surgery.

Methods: Among 479 patients who underwent ≥5-level fusion surgery for ASD, the focus was on those who experienced R-PJF at any time or did not experience R-PJF during a follow-up duration of ≥1 year. PJF was defined as a proximal junctional angle (PJA) ≥28° plus a difference in PJA ≥22° or performance of revision surgery regardless of PJA degree. The patients were divided into 2 groups according to R-PJF development: no R-PJF and R-PJF groups. Risk factors were evaluated focusing on patient, surgical, and radiographic factors at the index surgery as well as at the revision surgery.

Results: Of the 60 patients in the final study cohort, 24 (40%) experienced R-PJF. Significant risk factors included greater postoperative sagittal vertical axis (OR = 1.044), overcorrection relative to age-adjusted pelvic incidence-lumbar lordosis (PI-LL; OR = 7.794) at the index surgery, a greater total sum of the proximal junctional kyphosis severity scale (OR = 1.145), and no use of the upper instrumented vertebra cement (OR = 5.494) at the revision surgery.

Conclusions: We revealed that the greater postoperative sagittal vertical axis and overcorrection relative to age-adjusted pelvic incidence-lumbar lordosis at the index surgery, a greater proximal junctional kyphosis severity scale score, and no use of upper instrumented vertebra cement at the revision surgery were significant risk factors for R-PJF.

Clinical relevance: To reduce the risk of R-PJF after ASD surgery, avoiding under- and overcorrection during the initial surgery is recommended. Additionally, close assessment of the severity of PJF with timely intervention is crucial, and cement augmentation should be considered during revision surgery.

Level of evidence: 3:

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成人脊柱畸形手术后复发近端连接失败的风险因素:对 60 例因近端连接失败而接受融合扩展手术的患者进行分析。
背景:尽管有大量研究确定了近端连接失败(PJF)的风险因素,但复发性 PJF(R-PJF)的风险因素仍未得到很好的确定。因此,我们旨在确定成人脊柱畸形(ASD)手术后 R-PJF 的风险因素:方法:在 479 例因 ASD 而接受≥5 级融合手术的患者中,重点关注那些在任何时间经历过 R-PJF 或在随访时间≥1 年期间未经历过 R-PJF 的患者。PJF的定义是近端交界角(PJA)≥28°加上PJA差值≥22°或无论PJA程度如何都进行了翻修手术。根据 R-PJF 发展情况将患者分为两组:无 R-PJF 组和 R-PJF 组。对风险因素进行了评估,重点是指数手术和翻修手术中的患者、手术和放射学因素:最终研究队列中的 60 名患者中,有 24 人(40%)经历了 R-PJF。显著的风险因素包括:术后矢状纵轴较大(OR = 1.044)、指数手术时相对于年龄调整后骨盆入射角-腰椎前凸(PI-LL;OR = 7.794)的过度矫正、近端交界脊柱后凸严重程度量表总和较大(OR = 1.145)、翻修手术时未使用上部器械椎体骨水泥(OR = 5.494):我们发现,在指数手术中,相对于年龄调整后的骨盆发生率-腰椎前凸,术后矢状纵轴更大和过度矫正、近端交界处脊柱后凸严重程度量表评分更高以及翻修手术中未使用上部器械椎骨水泥是R-PJF的重要风险因素:为降低 ASD 手术后发生 R-PJF 的风险,建议在初次手术中避免矫正不足或矫正过度。此外,密切评估 PJF 的严重程度并及时进行干预至关重要,在翻修手术中应考虑增加骨水泥:3:
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来源期刊
CiteScore
3.10
自引率
0.00%
发文量
162
期刊介绍: The International Journal of Spine Surgery is the official scientific journal of ISASS, the International Intradiscal Therapy Society, the Pittsburgh Spine Summit, and the Büttner-Janz Spinefoundation, and is an official partner of the Southern Neurosurgical Society. The goal of the International Journal of Spine Surgery is to promote and disseminate online the most up-to-date scientific and clinical research into innovations in motion preservation and new spinal surgery technology, including basic science, biologics, and tissue engineering. The Journal is dedicated to educating spine surgeons worldwide by reporting on the scientific basis, indications, surgical techniques, complications, outcomes, and follow-up data for promising spinal procedures.
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