Abdominal Obesity-Metabolic Syndrome 3 Misclassified as Type 1 Diabetes Mellitus.

JCEM case reports Pub Date : 2024-08-06 eCollection Date: 2024-08-01 DOI:10.1210/jcemcr/luae120
Suhaib Radi, Lujain Bashamakh, Hayfa Mandourah, Sarah Alsharif
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Abstract

Age is no longer the most important differentiating feature between type 1 and type 2 diabetes, as obesity and metabolic syndrome are on the rise in the pediatric population. Here we present a case of a 30-year-old male individual initially diagnosed with uncontrolled type 1 diabetes mellitus (T1DM) since the age of 15, and treatment with high insulin doses has been unsuccessful. He was later identified as having abdominal obesity-metabolic syndrome 3 (AOMS3) based on strong family history and the presence of insulin resistance features. AOMS3 is characterized by early-onset coronary artery disease, central obesity, hypertension, and diabetes. Early detection of this condition is crucial to implement timely interventions and preventing the onset of complications.

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腹部肥胖-代谢综合征 3 被误诊为 1 型糖尿病。
年龄不再是区分 1 型糖尿病和 2 型糖尿病的最重要特征,因为肥胖和代谢综合征在儿童群体中呈上升趋势。我们在此介绍一例 30 岁男性患者的病例,他最初被诊断为自 15 岁以来一直未得到控制的 1 型糖尿病(T1DM),使用大剂量胰岛素治疗一直不成功。后来,他因家族遗传史和胰岛素抵抗特征而被确诊为腹型肥胖-代谢综合征 3(AOMS3)。腹型肥胖-代谢综合征 3 的特征是早发冠心病、中心性肥胖、高血压和糖尿病。及早发现这一病症对于及时采取干预措施和预防并发症的发生至关重要。
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