A probable cluster of premature birth and stillbirth caused by Leptospira interrogans serogroup Hebdomadis in an integrated swine farm in Nagasaki Prefecture, Japan.

IF 1.1 4区 农林科学 Q3 VETERINARY SCIENCES Journal of Veterinary Medical Science Pub Date : 2024-10-01 Epub Date: 2024-08-07 DOI:10.1292/jvms.24-0215
Yoshimi Terayama, Masashi Maeda, Yusuke Hata, Youhei Kawasaki, Nobuo Koizumi
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Abstract

In an integrated swine farm with 135 sows in Nagasaki Prefecture, premature births and stillbirths were observed in six sows in June and July 2023, and their etiology was investigated. Leptospiral flaB gene was detected in the kidney of one stillborn fetus and the placenta of its sow by nested PCR. Multilocus sequence typing revealed that the infecting strain was Leptospira interrogans ST118. In addition, leptospiral antigens were detected in lesions of the above tissues by immunohistochemical staining. The examined sow and several other sows in the farm had antibodies against serogroup Hebdomadis. These results suggested that L. interrogans serogroup Hebdomadis ST118 was the causative agent of premature births and stillbirths that occurred in this farm.

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日本长崎县一家综合养猪场可能发生由钩端螺旋体血清群 Hebdomadis 引起的早产和死胎群。
长崎县一个拥有 135 头母猪的综合养猪场在 2023 年 6 月和 7 月观察到 6 头母猪早产和死胎,并对其病因进行了调查。通过巢式聚合酶链式反应,在一个死胎的肾脏及其母猪胎盘中检测到钩端螺旋体 flaB 基因。多焦点序列分型显示,感染菌株为钩端螺旋体 ST118。此外,通过免疫组化染色,在上述组织的病变中检测到钩端螺旋体抗原。受检母猪和猪场中的其他几头母猪体内都有针对血清群 Hebdomadis 的抗体。这些结果表明,L. interrogans 血清群 Hebdomadis ST118 是导致该猪场发生早产和死胎的病原体。
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来源期刊
Journal of Veterinary Medical Science
Journal of Veterinary Medical Science 农林科学-兽医学
CiteScore
2.30
自引率
8.30%
发文量
230
审稿时长
9-18 weeks
期刊介绍: JVMS is a peer-reviewed journal and publishes a variety of papers on veterinary science from basic research to applied science and clinical research. JVMS is published monthly and consists of twelve issues per year. Papers are from the areas of anatomy, physiology, pharmacology, toxicology, pathology, immunology, microbiology, virology, parasitology, internal medicine, surgery, clinical pathology, theriogenology, avian disease, public health, ethology, and laboratory animal science. Although JVMS has played a role in publishing the scientific achievements of Japanese researchers and clinicians for many years, it now also accepts papers submitted from all over the world.
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