Min Cheng, Qin Liu, Haoyue Gan, Hangcheng Liu, Mei He
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引用次数: 0
Abstract
Background: The purpose of this study is to investigate the prevalence and risk factor of cognitive frailty in patients undergoing maintenance hemodialysis.
Methods: Systematically searched PubMed, EmBase, Web of Science, Cochrane Library, SinoMed, China Knowledge Resource Integrated Database, Wanfang Database, and Weipu Database from inception until January 1, 2024. Two researchers were independently screened and cross-checked. Stata 15.1 software was used to perform the meta-analysis.
Results: A total of 15 articles were included, including 5398 patients. The results showed that the prevalence of cognitive frailty in patients undergoing maintenance hemodialysis was 24%. Among them, age (odds ratio [OR] = 1.33, 95% CI [1.16, 1.53]), waist circumference (OR = 1.05, 95% CI [1.03, 1.08]), malnutrition (OR = 2.91, 95% CI [1.94, 4.35]), comorbidities (OR = 1.93, 95% CI [1.47, 2.54]), stroke history (OR = 2.94, 95% CI [1.72, 5.03]), and depression (OR = 3.26, 95% CI [1.91, 5.57]) were the main risk factors for cognitive frailty in patients undergoing maintenance hemodialysis. Education level (OR = 0.48, 95% CI [0.31, 0.73]) was protective factors for cognitive frailty in patients undergoing maintenance hemodialysis.
Conclusions: Current evidence showed that the prevalence of cognitive frailty in patients undergoing maintenance hemodialysis was high, and there were many risk factors. Therefore, early identification and intervention of cognitive frailty in maintenance hemodialysis patients should be carried out, which may be helpful to reduce the prevalence rate and occurrence of adverse events and improve the prognosis of patients.
背景：本研究旨在调查维持性血液透析患者认知虚弱的发生率和风险因素：本研究旨在探讨维持性血液透析患者认知虚弱的发生率和风险因素：系统检索PubMed、EmBase、Web of Science、Cochrane Library、SinoMed、中国知识资源整合数据库、万方数据库和维普数据库，检索时间从开始至2024年1月1日。两名研究人员独立筛选并交叉核对。使用Stata 15.1软件进行荟萃分析：共纳入 15 篇文章，包括 5398 名患者。结果显示，在接受维持性血液透析的患者中，认知虚弱的发生率为 24%。其中，年龄（几率比 [OR] = 1.33，95% CI [1.16，1.53]）、腰围（OR = 1.05，95% CI [1.03，1.08]）、营养不良（OR = 2.91，95% CI [1.94，4.35]）、合并症（OR = 1.93，95% CI [1。47，2.54]）、中风史（OR = 2.94，95% CI [1.72，5.03]）和抑郁（OR = 3.26，95% CI [1.91，5.57]）是维持性血液透析患者认知虚弱的主要危险因素。教育水平（OR = 0.48，95% CI [0.31，0.73]）是维持性血液透析患者认知功能衰弱的保护因素：目前的证据显示，在接受维持性血液透析的患者中，认知功能衰弱的发生率很高，而且存在许多风险因素。因此，应对维持性血液透析患者的认知功能虚弱进行早期识别和干预，这可能有助于降低不良事件的发生率和发生率，改善患者的预后。
期刊介绍：
Seminars in Dialysis is a bimonthly publication focusing exclusively on cutting-edge clinical aspects of dialysis therapy. Besides publishing papers by the most respected names in the field of dialysis, the Journal has unique useful features, all designed to keep you current:
-Fellows Forum
-Dialysis rounds
-Editorials
-Opinions
-Briefly noted
-Summary and Comment
-Guest Edited Issues
-Special Articles
Virtually everything you read in Seminars in Dialysis is written or solicited by the editors after choosing the most effective of nine different editorial styles and formats. They know that facts, speculations, ''how-to-do-it'' information, opinions, and news reports all play important roles in your education and the patient care you provide.
Alternate issues of the journal are guest edited and focus on a single clinical topic in dialysis.
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