Assessment of neural function recovery in premature infants at high risk of brain injury using amplitude integrated electroencephalography and GMs scales

IF 2.7 4区 医学 Q2 BIOCHEMICAL RESEARCH METHODS Journal of Neuroscience Methods Pub Date : 2024-08-08 DOI:10.1016/j.jneumeth.2024.110246
Chun Lin, Bo Chen, Zhiqiang Wang, Andi Zou, Minghui Ke
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Abstract

Preterm infants are a high-risk group for brain injury, and it is important to evaluate the neurological recovery of preterm infants. Therefore, this paper evaluates the neurological recovery in preterm infants at high risk of brain injury by amplitude-integrated EEG and GMs scale. The study collected basic information on preterm infants and performed amplitude integrated EEG examination and GMs scale evaluation. Amplitude integrated EEG examination attaches electrodes using multielectrode arrays onto specific areas of the premature head to record brain wave activity to monitor electrical activity in the preterm brain in real time and amplify and process through the signals received by the electrodes to obtain more detailed EEG data. The GMs scale evaluates the developmental and functional status of the child and allows an objective assessment of the development and recovery of neurological function by observing their performance in motor, language, cognition, and social interaction. Analysis of the data by statistical processing. The results showed that early brain injury was evident in high-risk infants. Amplitude integrated EEG parameters can have some predictive value for brain injury. There were also differences in GMs scale assessment between brain injury and non-brain injury. Amplitude integrated EEG combined with GMs scale has certain value in predicting brain injury and can provide an important basis for early intervention in children with preterm brain injury and help to improve their neurodevelopmental outcome.

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使用振幅综合脑电图和 GMs 量表评估脑损伤高风险早产儿的神经功能恢复情况。
早产儿是脑损伤的高危人群,因此评估早产儿的神经功能恢复情况非常重要。因此,本文通过振幅积分脑电图和GMs量表评估脑损伤高危早产儿的神经功能恢复情况。研究收集了早产儿的基本信息,并进行了振幅整合脑电图检查和 GMs 量表评估。振幅综合脑电图检查是利用多电极阵列将电极安装在早产儿头部的特定区域,以记录脑波活动,从而实时监测早产儿的脑电活动,并对电极接收到的信号进行放大和处理,以获得更详细的脑电图数据。GMs 量表可评估儿童的发育和功能状况,通过观察儿童在运动、语言、认知和社会交往方面的表现,客观评估其神经功能的发育和恢复情况。通过统计处理对数据进行分析。结果显示,高风险婴儿的早期脑损伤明显。振幅综合脑电图参数对脑损伤有一定的预测价值。脑损伤和非脑损伤的 GMs 量表评估也存在差异。振幅综合脑电图结合GMs量表对脑损伤有一定的预测价值,可为早产儿脑损伤的早期干预提供重要依据,有助于改善其神经发育结局。
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来源期刊
Journal of Neuroscience Methods
Journal of Neuroscience Methods 医学-神经科学
CiteScore
7.10
自引率
3.30%
发文量
226
审稿时长
52 days
期刊介绍: The Journal of Neuroscience Methods publishes papers that describe new methods that are specifically for neuroscience research conducted in invertebrates, vertebrates or in man. Major methodological improvements or important refinements of established neuroscience methods are also considered for publication. The Journal''s Scope includes all aspects of contemporary neuroscience research, including anatomical, behavioural, biochemical, cellular, computational, molecular, invasive and non-invasive imaging, optogenetic, and physiological research investigations.
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