{"title":"A Systematic Review and Meta-Analysis of <i>Aeromonas</i>-Associated Diarrhea Among Children in Asia.","authors":"Hamid Sadeghi, Masoumeh Aslanimehr, Farhad Nikkhahi, Roya Safari, Majid Vafaie, Saeideh Gholamzadeh Khoei","doi":"10.1089/sur.2024.090","DOIUrl":null,"url":null,"abstract":"<p><p><b><i>Background:</i></b> Diarrheal illness is a prominent public health worry in developing countries, resulting in high mortality among children. Sociodemographic characteristics and geographic settings are the main effective factors for the increased incidence of childhood diarrhea. <i>Aeromonas</i> is a neglected organism capable of causing dysentery and diarrhea. The aim of this systematic review and meta-analysis was to determine the prevalence of <i>Aeromonas</i> as an agent in the causation of diarrhea in Asian children. <b><i>Methods:</i></b> We conducted a systematic review using Web of Science, PubMed, Wiley Online Library, Science Direct, and Google Scholar for peer-reviewed articles published between January 2000 and February 2023. We considered studies that found <i>Aeromonas</i> in diarrheal stool. A random-effects model was used to determine the pooled prevalence of <i>Aeromonas</i>. <b><i>Results:</i></b> Our search returned 2,057 articles, with 17 articles from seven Asian nations being included in the systematic review. The pooled prevalence of <i>Aeromonas</i> was 4.5% (95% confidence interval [CI]: 2.9%-6.8%), with heterogeneity (<i>I</i><sup>2</sup> = 96.85; p < 0.001). There was a greater prevalence in areas with high population living in poverty (12.2%; 95% CI: 5.8%-24%) and lower-middle-income countries (5.0%; 95% CI: 2.7%-9.0%). In addition, the prevalence of <i>Aeromonas</i> was greater in South Asia (10.0%; 95% CI: 5.6%-17.2%), in India (12.9%; 95% CI: 6.8%-23%), and in countries with open defecation rate of 5%-25% (11.3%; 95% CI: 6.3%-19.2%). <b><i>Conclusion:</i></b> The prevalence of <i>Aeromonas</i>-associated diarrhea in children in Asia estimated in the present study highlighted the high burden of <i>Aeromonas</i> in some parts of Asia.</p>","PeriodicalId":22109,"journal":{"name":"Surgical infections","volume":null,"pages":null},"PeriodicalIF":1.4000,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Surgical infections","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1089/sur.2024.090","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/8/12 0:00:00","PubModel":"Epub","JCR":"Q4","JCRName":"INFECTIOUS DISEASES","Score":null,"Total":0}
引用次数: 0
Abstract
Background: Diarrheal illness is a prominent public health worry in developing countries, resulting in high mortality among children. Sociodemographic characteristics and geographic settings are the main effective factors for the increased incidence of childhood diarrhea. Aeromonas is a neglected organism capable of causing dysentery and diarrhea. The aim of this systematic review and meta-analysis was to determine the prevalence of Aeromonas as an agent in the causation of diarrhea in Asian children. Methods: We conducted a systematic review using Web of Science, PubMed, Wiley Online Library, Science Direct, and Google Scholar for peer-reviewed articles published between January 2000 and February 2023. We considered studies that found Aeromonas in diarrheal stool. A random-effects model was used to determine the pooled prevalence of Aeromonas. Results: Our search returned 2,057 articles, with 17 articles from seven Asian nations being included in the systematic review. The pooled prevalence of Aeromonas was 4.5% (95% confidence interval [CI]: 2.9%-6.8%), with heterogeneity (I2 = 96.85; p < 0.001). There was a greater prevalence in areas with high population living in poverty (12.2%; 95% CI: 5.8%-24%) and lower-middle-income countries (5.0%; 95% CI: 2.7%-9.0%). In addition, the prevalence of Aeromonas was greater in South Asia (10.0%; 95% CI: 5.6%-17.2%), in India (12.9%; 95% CI: 6.8%-23%), and in countries with open defecation rate of 5%-25% (11.3%; 95% CI: 6.3%-19.2%). Conclusion: The prevalence of Aeromonas-associated diarrhea in children in Asia estimated in the present study highlighted the high burden of Aeromonas in some parts of Asia.
期刊介绍:
Surgical Infections provides comprehensive and authoritative information on the biology, prevention, and management of post-operative infections. Original articles cover the latest advancements, new therapeutic management strategies, and translational research that is being applied to improve clinical outcomes and successfully treat post-operative infections.
Surgical Infections coverage includes:
-Peritonitis and intra-abdominal infections-
Surgical site infections-
Pneumonia and other nosocomial infections-
Cellular and humoral immunity-
Biology of the host response-
Organ dysfunction syndromes-
Antibiotic use-
Resistant and opportunistic pathogens-
Epidemiology and prevention-
The operating room environment-
Diagnostic studies