ANDROID and A/G ratio are correlated with sarcopenia among type 2 diabetes patients.

IF 4.3 3区材料科学 Q1 ENGINEERING, ELECTRICAL & ELECTRONIC ACS Applied Electronic Materials Pub Date : 2024-08-07 eCollection Date: 2024-01-01 DOI:10.1177/20420188241269181

Dongxiao Zhang, Chen Li, Wenchao Hu, Lanjie He

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Abstract

Background: Fat distribution plays an important role in impaired glucose tolerance. Android adiposity (ANDROID) and gynoid adiposity (GYNOID) have been proven to be linked with insulin resistance. A higher risk of sarcopenia is associated with type 2 diabetes mellitus (T2DM). In this study, ANDROID, GYNOID, and ANDROID to GYNOID ratios (A/G ratios) were evaluated in T2DM patients to determine if they were associated with sarcopenia.

Methods: We recruited 1086 T2DM patients, measured skeletal muscle index (SMI), ANDROID, GYNOID, and collected clinical data.

Results: T2DM patients with 119 male subjects had sarcopenia (20.24%), and 72 female subjects had sarcopenia (16.51%). All patients with T2DM who had high ANDROID and A/G ratios were at a reduced risk of sarcopenia. The SMI showed a correlation with ANDROID and A/G ratios among subjects with T2DM.

Conclusion: ANDROID and A/G ratios are inversely related to sarcopenia in T2DM patients.

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ANDROID 和 A/G 比率与 2 型糖尿病患者的肌肉疏松症有关。

背景：脂肪分布在糖耐量受损中起着重要作用。安卓脂肪症（ANDROID）和妇科脂肪症（GYNOID）已被证实与胰岛素抵抗有关。较高的肌肉疏松症风险与 2 型糖尿病（T2DM）有关。本研究评估了 T2DM 患者的 ANDROID、GYNOID 以及 ANDROID 与 GYNOID 比率（A/G 比率），以确定它们是否与肌肉疏松症相关：我们招募了1086名T2DM患者，测量了骨骼肌指数（SMI）、ANDROID、GYNOID，并收集了临床数据：结果：119 名男性 T2DM 患者患有肌肉疏松症（20.24%），72 名女性患者患有肌肉疏松症（16.51%）。所有 ANDROID 和 A/G 比率较高的 T2DM 患者患肌肉疏松症的风险均有所降低。在患有 T2DM 的受试者中，SMI 与 ANDROID 和 A/G 比率存在相关性：结论：ANDROID 和 A/G 比率与 T2DM 患者的肌少症成反比。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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