Cardiogenic shock in the context of acute coronary syndromes in Latin America (“LATIN Shock”)

IF 3 3区医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Current Problems in Cardiology Pub Date : 2024-08-10 DOI:10.1016/j.cpcardiol.2024.102745

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Abstract

Cardiogenic shock (CS) is a serious complication of heart attack and constitutes one of its main causes of death. To date, there is no data on its treatment and evolution in Latin America.

Objectives

To know the clinical characteristics, treatment strategies, evolution and in-hospital mortality of CS in Latin America.

Materials and methods

This is a prospective, multicenter registry of patients hospitalized with CS in the context of acute coronary syndromes (ACS) with and without ST segment elevation for 24 months.

Results

41 Latin American centers participated incorporating patients during the period between October 2021 and September 2023. 278 patients were included. Age: 66 (59-75) years, 70.1 % men. 74.8 % of the cases correspond to ACS with ST elevation, 14.4 % to ACS without ST elevation, 5.7 % to right ventricular infarction and 5.1 % to mechanical complications. CS was present from admission in 60 % of cases. Revascularization: 81.3 %, inotropic use: 97.8 %, ARM: 52.5 %, Swan Ganz: 17 %, intra-aortic balloon pump: 22.2 %. Overall in-hospital mortality was 52.7 %, with no differences between ACS with or without ST.

Conclusions

Morbidity and mortality is very high despite the high reperfusion used.

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拉丁美洲急性冠状动脉综合征背景下的心源性休克（"LATIN 休克"）。

心源性休克（CS）是心脏病发作的一种严重并发症，也是导致死亡的主要原因之一。迄今为止，拉丁美洲还没有关于其治疗和演变的数据：了解拉丁美洲 CS 的临床特征、治疗策略、演变情况和院内死亡率：这是一项前瞻性多中心登记，对象为急性冠状动脉综合征（ACS）住院患者，包括 ST 段抬高和非 ST 段抬高患者，为期 24 个月：结果：41 个拉丁美洲中心在 2021 年 10 月至 2023 年 9 月期间参与了患者登记。共纳入 278 名患者。年龄：66（59-75）岁，70.1% 为男性。74.8%的病例为ST段抬高的ACS，14.4%为无ST段抬高的ACS，5.7%为右心室梗死，5.1%为机械并发症。60%的病例在入院时就存在CS。血管重建率：81.3%，肌力药物使用率：97.8%，ARM使用率：97.8%：97.8%，ARM：52.5%，Swan Ganz：17%，主动脉内球囊泵：22.2%。院内总死亡率为 52.7%，有 ST 或无 ST 的 ACS 之间没有差异：结论：尽管使用了大量再灌注，但发病率和死亡率仍然很高。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current Problems in Cardiology 医学-心血管系统

CiteScore

4.80

自引率

2.40%

发文量

392

审稿时长

6 days

期刊介绍： Under the editorial leadership of noted cardiologist Dr. Hector O. Ventura, Current Problems in Cardiology provides focused, comprehensive coverage of important clinical topics in cardiology. Each monthly issues, addresses a selected clinical problem or condition, including pathophysiology, invasive and noninvasive diagnosis, drug therapy, surgical management, and rehabilitation; or explores the clinical applications of a diagnostic modality or a particular category of drugs. Critical commentary from the distinguished editorial board accompanies each monograph, providing readers with additional insights. An extensive bibliography in each issue saves hours of library research.