A. Kwong, A. Edmondson-Stait, Eileen Xu, Ellen J. Thompson, Richard M. A. Parker, Ahmed Elhakeem, L. Romaniuk, Rebecca M. Pearson, Kate Tilling, Thalia C. Eley, McIntosh Andrew M, Heather C. Whalley
{"title":"TIDAL: Tool to Implement Developmental Analysis of Longitudinal data","authors":"A. Kwong, A. Edmondson-Stait, Eileen Xu, Ellen J. Thompson, Richard M. A. Parker, Ahmed Elhakeem, L. Romaniuk, Rebecca M. Pearson, Kate Tilling, Thalia C. Eley, McIntosh Andrew M, Heather C. Whalley","doi":"10.1101/2024.08.12.24311854","DOIUrl":null,"url":null,"abstract":"Motivation: Growth curve modelling is one method used to model trajectories of traits and behaviours over time. However, accessing, analysing and interpreting trajectories requires statistical expertise, thereby creating potential barriers for users to implement and understand longitudinal traits. TIDAL is a user-friendly research tool designed to facilitate trajectory modelling by improving access, analysis and interpretation of trajectory and longitudinal data. Implementation: TIDAL is available in two formats: an R package and an online Shiny application. The R package can be used offline, negating the need to upload potentially sensitive data. General features: TIDAL includes all the main steps of trajectory analysis including: 1) data preparation, (converting data from wide to long format); 2) data exploration, via basic plots and descriptive information; 3) analysis of trajectories using mixed effects modelling, interpretation of results, visualisation of trajectories, and extraction of key features (scores at different ages; area under the curve); and 4) interactions to derive population specific trajectories, combined with all the above. TIDAL is built with a simple graphical interface to guide users through each step. R syntax accompanies each step. Availability: Both versions of TIDAL can be found here: [https://tidal-modelling.github.io/].","PeriodicalId":18505,"journal":{"name":"medRxiv","volume":"37 8","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"medRxiv","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1101/2024.08.12.24311854","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Motivation: Growth curve modelling is one method used to model trajectories of traits and behaviours over time. However, accessing, analysing and interpreting trajectories requires statistical expertise, thereby creating potential barriers for users to implement and understand longitudinal traits. TIDAL is a user-friendly research tool designed to facilitate trajectory modelling by improving access, analysis and interpretation of trajectory and longitudinal data. Implementation: TIDAL is available in two formats: an R package and an online Shiny application. The R package can be used offline, negating the need to upload potentially sensitive data. General features: TIDAL includes all the main steps of trajectory analysis including: 1) data preparation, (converting data from wide to long format); 2) data exploration, via basic plots and descriptive information; 3) analysis of trajectories using mixed effects modelling, interpretation of results, visualisation of trajectories, and extraction of key features (scores at different ages; area under the curve); and 4) interactions to derive population specific trajectories, combined with all the above. TIDAL is built with a simple graphical interface to guide users through each step. R syntax accompanies each step. Availability: Both versions of TIDAL can be found here: [https://tidal-modelling.github.io/].