A preliminary investigation into the effects of a soluble dietary fibre and mineral formulation on post-prandial glucose regulation and satiation in healthy adults
{"title":"A preliminary investigation into the effects of a soluble dietary fibre and mineral formulation on post-prandial glucose regulation and satiation in healthy adults","authors":"Michael M Haynes","doi":"10.1101/2024.08.03.606479","DOIUrl":null,"url":null,"abstract":"Prevalence of obesity and overweight has steadily increased over the past decade, urging the development, and refining of various methods of intervention to combat the epidemic. Glucomannan is a dietary fibre with gelling properties, contributing to satiety. Chromium picolinate is an artificial additive, initially suggested to be an essential trace element, contributing to lipid and carbohydrate metabolism. Fructo-oligosaccharides are among a group of calorie free prebiotics, contributing to mineral absorption. Here, we are presenting an open label, preliminary investigation, to explore the effect of a formulation containing glucomannan, chromium picolinate and fructo-oligosaccharides on post-prandial blood glucose modulation and hunger and satiation in 17 adults (Mean ± SD: age 26.35 ± 5.18 years; height 171 ± 11.22 cm; body weight 73.24 ± 13.23 kg; BMI 24.89 ± 2.72 kg/m<sup>2</sup>). Data have shown significant reductions in feelings of hunger (P = > .001), and desire to eat (P= > .001), with no significant effect on blood glucose control. These findings have suggested use of this formulation in dietary intervention, through controlling obesity related parameters.","PeriodicalId":501557,"journal":{"name":"bioRxiv - Physiology","volume":"10 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"bioRxiv - Physiology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1101/2024.08.03.606479","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Prevalence of obesity and overweight has steadily increased over the past decade, urging the development, and refining of various methods of intervention to combat the epidemic. Glucomannan is a dietary fibre with gelling properties, contributing to satiety. Chromium picolinate is an artificial additive, initially suggested to be an essential trace element, contributing to lipid and carbohydrate metabolism. Fructo-oligosaccharides are among a group of calorie free prebiotics, contributing to mineral absorption. Here, we are presenting an open label, preliminary investigation, to explore the effect of a formulation containing glucomannan, chromium picolinate and fructo-oligosaccharides on post-prandial blood glucose modulation and hunger and satiation in 17 adults (Mean ± SD: age 26.35 ± 5.18 years; height 171 ± 11.22 cm; body weight 73.24 ± 13.23 kg; BMI 24.89 ± 2.72 kg/m2). Data have shown significant reductions in feelings of hunger (P = > .001), and desire to eat (P= > .001), with no significant effect on blood glucose control. These findings have suggested use of this formulation in dietary intervention, through controlling obesity related parameters.