A preliminary investigation into the effects of a soluble dietary fibre and mineral formulation on post-prandial glucose regulation and satiation in healthy adults

Michael M Haynes
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Abstract

Prevalence of obesity and overweight has steadily increased over the past decade, urging the development, and refining of various methods of intervention to combat the epidemic. Glucomannan is a dietary fibre with gelling properties, contributing to satiety. Chromium picolinate is an artificial additive, initially suggested to be an essential trace element, contributing to lipid and carbohydrate metabolism. Fructo-oligosaccharides are among a group of calorie free prebiotics, contributing to mineral absorption. Here, we are presenting an open label, preliminary investigation, to explore the effect of a formulation containing glucomannan, chromium picolinate and fructo-oligosaccharides on post-prandial blood glucose modulation and hunger and satiation in 17 adults (Mean ± SD: age 26.35 ± 5.18 years; height 171 ± 11.22 cm; body weight 73.24 ± 13.23 kg; BMI 24.89 ± 2.72 kg/m2). Data have shown significant reductions in feelings of hunger (P = > .001), and desire to eat (P= > .001), with no significant effect on blood glucose control. These findings have suggested use of this formulation in dietary intervention, through controlling obesity related parameters.
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可溶性膳食纤维和矿物质配方对健康成年人餐后血糖调节和饱腹感影响的初步研究
过去十年来,肥胖症和超重症的发病率持续上升,促使人们开发和改进各种干预方法,以应对这一流行病。葡甘露聚糖是一种具有胶凝特性的膳食纤维,有助于产生饱腹感。吡啶甲酸铬是一种人工添加剂,最初被认为是一种重要的微量元素,有助于脂质和碳水化合物的新陈代谢。果寡糖是一类不含热量的益生元,有助于矿物质的吸收。在此,我们将介绍一项开放标签的初步调查,以探讨含有葡甘露聚糖、吡啶甲酸铬和果寡糖的配方对 17 名成年人(平均值(± SD):年龄 26.35 ± 5.18 岁;身高 171 ± 11.22 厘米;体重 73.24 ± 13.23 千克;体重指数 24.89 ± 2.72 千克/平方米)餐后血糖调节以及饥饿和饱腹感的影响。数据显示,饥饿感(P= >.001)和进食欲望(P= >.001)明显降低,但对血糖控制无明显影响。这些研究结果表明,通过控制肥胖相关参数,该配方可用于饮食干预。
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