I2/CAN as an efficient reagent for the direct oxidation of tertiary Csp3-H to Csp3-OH: Synthesis of bis(N-methyl-7-azaindol-3-yl) (phenyl) methanol from 3,3′-(phenyl methylene)-bis(N-methyl-7-azaindole)
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引用次数: 0
Abstract
I2/CAN has emerged as a powerful and efficient oxidizing agent for direct tertiary CH oxidation of 3,3′-(phenyl methylene) bis(N-methyl-7-azaindole) under mild conditions to form bis(N-methyl-7-azaindol-3-yl) (phenyl)methanol in quantitative yield. Further, based on control experiments, a plausible mechanism and characterization of products including XRD are described. Synthetic transformation for bis(N-methyl-7-azaindol-3-yl) (phenyl) methanol is achieved by thionation.
期刊介绍：
Tetrahedron Letters provides maximum dissemination of outstanding developments in organic chemistry. The journal is published weekly and covers developments in techniques, structures, methods and conclusions in experimental and theoretical organic chemistry. Rapid publication of timely and significant research results enables researchers from all over the world to transmit quickly their new contributions to large, international audiences.
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