GAMBAS -- Fast Beam Arrangement Selection for Proton Therapy using a Nearest Neighbour Model

Renato Bellotti, Nicola Bizzocchi, Antony J. Lomax, Andreas Adelmann, Damien C. Weber, Jan Hrbacek
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Abstract

Purpose: Beam angle selection is critical in proton therapy treatment planning, yet automated approaches remain underexplored. This study presents and evaluates GAMBAS, a novel, fast machine learning model for automatic beam angle selection. Methods: The model extracts a predefined set of anatomical features from a patient's CT and structure contours. Using these features, it identifies the most similar patient from a training database and suggests that patient's beam arrangement. A retrospective study with 19 patients was conducted, comparing this model's suggestions to human planners' choices and randomly selected beam arrangements from the training dataset. An expert treatment planner evaluated the plans on quality (scale 1-5), ranked them, and guessed the method used. Results: The number of acceptable (score 4 or 5) plans was comparable between human-chosen 17 (89%) and model-selected 16(84%) beam arrangements. The fully automatic treatment planning took between 4 - 7 min (mean 5 min). Conclusion: The model produces beam arrangements of comparable quality to those chosen by human planners, demonstrating its potential as a fast tool for quality assurance and patient selection, although it is not yet ready for clinical use.
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GAMBAS -- 利用近邻模型为质子治疗快速选择射束排列
目的:束角选择在质子治疗治疗计划中至关重要,但自动方法仍未得到充分探索。本研究介绍并评估了用于自动束角选择的新型快速机器学习模型 GAMBAS。方法:该模型从患者的 CT 和结构轮廓中提取一组预定义的解剖特征。利用这些特征,它能从训练数据库中识别出最相似的患者,并建议该患者的波束安排。对 19 名患者进行了回顾性研究,将该模型的建议与人类规划师的选择以及从训练数据集中随机选择的波束排列进行了比较。一位治疗计划专家对计划的质量(1-5 级)进行了评估,对计划进行了排名,并猜测了所使用的方法。结果:人工选择的 17 个(89%)和模型选择的 16 个(84%)光束排列方案中,可接受(4 分或 5 分)的方案数量相当。全自动治疗规划耗时 4-7 分钟(平均 5 分钟)。结论该模型产生的射束排列质量与人工规划者选择的射束排列质量相当,表明它有潜力成为质量保证和患者选择的快速工具,尽管它还不能用于临床。
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