012 ANB032, an investigational BTLA agonist monoclonal antibody, reduced T cell proliferation, inflammatory cytokine secretion, and prevented graft-versus-host disease (GvHD) in a mouse model

IF 5.7 2区医学 Q1 DERMATOLOGY Journal of Investigative Dermatology Pub Date : 2024-08-01 DOI:10.1016/j.jid.2024.06.028

E. Hare, M. Hsu, C. Schendel, C. Haines, P. Soroosh, S. Parmley, P. Lizzul, M. Dahl

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012 ANB032 是一种正在研究的 BTLA 激动剂单克隆抗体，可在小鼠模型中减少 T 细胞增殖、炎性细胞因子分泌并预防移植物抗宿主疾病（GvHD）。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Investigative Dermatology 医学-皮肤病学

CiteScore

8.70

自引率

4.60%

发文量

1610

审稿时长

2 months

期刊介绍： Journal of Investigative Dermatology (JID) publishes reports describing original research on all aspects of cutaneous biology and skin disease. Topics include biochemistry, biophysics, carcinogenesis, cell regulation, clinical research, development, embryology, epidemiology and other population-based research, extracellular matrix, genetics, immunology, melanocyte biology, microbiology, molecular and cell biology, pathology, percutaneous absorption, pharmacology, photobiology, physiology, skin structure, and wound healing

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