Macroporous polymeric resin for the purification of flavonoids from medicinal plants: A review

IF 2.8 3区工程技术 Q2 CHEMISTRY, ANALYTICAL Journal of separation science Pub Date : 2024-08-12 DOI:10.1002/jssc.202400372

Raghad Yousef Ali Aljawarneh, Mohamad Shazeli Che Zain, Fauziahanim Zakaria

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Abstract

The purification of flavonoids using the macroporous polymer resin method has gained attention in recent years due to its simplicity, precision, cost-effectiveness, and the ability to separate flavonoids from other constituents. Several studies have been conducted to investigate the efficiency and effectiveness of macroporous polymer resin in purifying flavonoids from various plant sources. This review aims to evaluate the existing literature on macroporous polymer resin purification of flavonoids and provide a comprehensive analysis of the current research trends and advancements in this field. It also highlights the importance of optimizing the adsorption parameters and conditions such as resin type, resin concentration, pH, and temperature for efficient purification of flavonoids using macroporous polymer resin. The key findings of this review reveal that macroporous resins with weak polarity, large surface areas, and pore diameters have a stronger adsorption capacity for flavonoids compared to polar resins. Furthermore, ultrasonic-solvent assisted extraction often combines with macroporous resin for effective the extraction and purification of flavonoids.

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从药用植物中提纯黄酮类化合物的大孔聚合树脂：综述。

近年来，使用大孔聚合物树脂法提纯黄酮类化合物因其简便、精确、成本效益高以及能将黄酮类化合物与其他成分分离而备受关注。已有多项研究探讨了大孔聚合物树脂从各种植物来源中提纯黄酮类化合物的效率和效果。本综述旨在评估有关大孔聚合物树脂提纯类黄酮的现有文献，并全面分析该领域当前的研究趋势和进展。综述还强调了优化吸附参数和条件（如树脂类型、树脂浓度、pH 值和温度）对于利用大孔聚合物树脂高效纯化黄酮类化合物的重要性。本综述的主要发现表明，与极性树脂相比，具有弱极性、大表面积和孔径的大孔树脂对黄酮类化合物具有更强的吸附能力。此外，超声波溶剂辅助萃取通常与大孔树脂相结合，可有效萃取和纯化黄酮类化合物。

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来源期刊

Journal of separation science 化学-分析化学

CiteScore

6.30

自引率

16.10%

发文量

408

审稿时长

1.8 months

期刊介绍： The Journal of Separation Science (JSS) is the most comprehensive source in separation science, since it covers all areas of chromatographic and electrophoretic separation methods in theory and practice, both in the analytical and in the preparative mode, solid phase extraction, sample preparation, and related techniques. Manuscripts on methodological or instrumental developments, including detection aspects, in particular mass spectrometry, as well as on innovative applications will also be published. Manuscripts on hyphenation, automation, and miniaturization are particularly welcome. Pre- and post-separation facets of a total analysis may be covered as well as the underlying logic of the development or application of a method.