Virtual non-contrast images in photon-counting computed tomography: impact of different contrast phases.

IF 1.1 4区 医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Acta radiologica Pub Date : 2024-09-01 Epub Date: 2024-08-14 DOI:10.1177/02841851241271202
Eva Laurin Gadsbøll, Marie-Louise Aurumskjöld, Fredrik Holmquist, Erik Baubeta
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Abstract

Background: Photon-counting computed tomography (PCCT) enables new ways of image reconstruction, e.g. material decomposition and creation of virtual non-contrast (VNC) series with higher resolution and lower radiation dose than standard computed tomography (CT). Clinical experiences of this are limited.

Purpose: To compare true non-contrast (TNC) series with VNC series derived from non-enhanced (VNCu), arterial phase (VNCa) and portal venous phase (VNCv) in clinically approved PCCT.

Material and methods: A total of 45 clinical, tri-phasic abdominal CT scans from the PCCT Naetom Alpha, between February 2022 and November 2022, were retrospectively assessed. Placing a region of interest in six different locations in each VNC series - right liver parenchyma, left liver parenchyma, spleen, aorta, erector spinae muscle, and in the subcutaneous fat - absolute Hounsfield values (HU) and standard deviations (SD) were collected. Differences in HU (ΔHU) were compared and statistically analyzed.

Results: Statistically significant differences between VNC and TNC were seen in all measurements, with the largest difference in the subcutaneous fat and the smallest difference in the erector spinae muscle. Only small differences were seen between VNCa and VNCv, where the largest differences were seen in the left and right liver lobes.

Conclusion: VNC images from the first-generation clinically approved PCCT showed a significant difference between VNC and TNC images. The differences vary with the type of tissue. Only small differences were seen depending from which contrast phase the VNC was derived.

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光子计数计算机断层扫描中的虚拟非对比图像:不同对比阶段的影响。
背景:与标准计算机断层扫描(CT)相比,光子计数计算机断层扫描(PCCT)可实现新的图像重建方式,如材料分解和创建虚拟非对比(VNC)系列,具有更高的分辨率和更低的辐射剂量。目的:比较真正的非对比(TNC)序列与临床认可的 PCCT 中非增强(VNCu)、动脉期(VNCa)和门静脉期(VNCv)的 VNC 序列:回顾性评估了 2022 年 2 月至 2022 年 11 月期间 PCCT Naetom Alpha 共 45 次临床三相腹部 CT 扫描。在每个 VNC 系列的六个不同位置(右肝实质、左肝实质、脾脏、主动脉、竖脊肌和皮下脂肪)放置感兴趣区,收集绝对 Hounsfield 值(HU)和标准偏差(SD)。对 HU 的差异(ΔHU)进行比较和统计分析:结果:在所有测量中,VNC 和 TNC 之间的差异都具有统计学意义,其中皮下脂肪的差异最大,竖脊肌的差异最小。VNCa 和 VNCv 之间只有微小差异,其中左右肝叶的差异最大:结论:经临床批准的第一代 PCCT 的 VNC 图像显示,VNC 和 TNC 图像之间存在显著差异。差异因组织类型而异。根据 VNC 的对比相位不同,差异也很小。
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来源期刊
Acta radiologica
Acta radiologica 医学-核医学
CiteScore
2.70
自引率
0.00%
发文量
170
审稿时长
3-8 weeks
期刊介绍: Acta Radiologica publishes articles on all aspects of radiology, from clinical radiology to experimental work. It is known for articles based on experimental work and contrast media research, giving priority to scientific original papers. The distinguished international editorial board also invite review articles, short communications and technical and instrumental notes.
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