Risk Factors for Depression Among Middle-Aged to Older People Living With HIV in Lima, Peru.

IF 2.2 Q3 INFECTIOUS DISEASES Journal of the International Association of Providers of AIDS Care Pub Date : 2024-01-01 DOI:10.1177/23259582241273452

Virgilio E Failoc-Rojas, Dan Tong Jia, Marcela Gil-Zacarias, Alana Latorre, Robinson Cabello, Patricia J Garcia, Monica M Diaz

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Abstract

Introduction: Depression is prevalent among aging people living with HIV (PLWH) worldwide. We sought to identify depression risk factors among a group of middle-aged and older PLWH in Lima, Peru.

Materials and methods: We assessed risk factors for depression among PLWH over age 40 receiving care in an HIV clinic in Lima, Peru. The Patient Health Questionnaire-9 (PHQ-9) was administered. We performed descriptive statistics and logistic regression analyses.

Results: Mean age was 51.7 ± 7.7 years with 15.3% females. One-quarter of participants had depression with higher frequency in females. Risk factors that significantly increased the risk of depression included female sex (adjusted prevalence ratio [aPR] = 2.19 [95%CI 1.07-4.49]), currently smoking (aPR = 2.25 [95%CI 1.15-4.43]), and prior opportunistic infection (aPR = 2.24 [95%CI 1.05-4.76]).

Discussion: Our study demonstrates that PLWH who are female, current smokers, or had an opportunistic infection have higher risk of depression. Identifying PLWH at-risk for depression is key to early mental health interventions.

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秘鲁利马中老年艾滋病病毒感染者抑郁的风险因素。

简介抑郁症在全球老年艾滋病病毒感染者（PLWH）中十分普遍。我们试图在秘鲁利马的一群中老年艾滋病病毒感染者中找出抑郁的风险因素：我们评估了在秘鲁利马一家艾滋病诊所接受治疗的 40 岁以上 PLWH 中的抑郁风险因素。我们采用了患者健康问卷-9（PHQ-9）。我们进行了描述性统计和逻辑回归分析：平均年龄为 51.7 ± 7.7 岁，女性占 15.3%。四分之一的参与者患有抑郁症，其中女性患者比例较高。显着增加抑郁风险的风险因素包括女性（调整患病率比 [aPR] = 2.19 [95%CI 1.07-4.49]）、目前吸烟（aPR = 2.25 [95%CI 1.15-4.43]）和既往机会性感染（aPR = 2.24 [95%CI 1.05-4.76]）：我们的研究表明，女性、目前吸烟或曾有机会性感染的 PLWH 患抑郁症的风险更高。发现有抑郁风险的 PLWH 是早期心理健康干预的关键。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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