Generalised models of the vertebrate eye.

IF 2.8 3区 医学 Q1 OPHTHALMOLOGY Ophthalmic and Physiological Optics Pub Date : 2024-11-01 Epub Date: 2024-08-13 DOI:10.1111/opo.13376
Jos J Rozema
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Abstract

Purpose: To present a set of closed-form analytical equations to create a consistent eye model balance based on clinically measured input parameters in a single step. These models complement the existing iterative approaches in the literature.

Methods: Two different approaches are presented, both considering the cornea and lens as equivalent thin lenses. The first, called the Gaussian model, starts by defining the refractive error as the difference between the axial power (or dioptric distance) and the whole eye power, which can be expanded by filling in the formulas for each power. The resulting equation can be solved for either the refractive error, axial length, corneal power, lens power or the distance between the cornea and the lens as a function of the other four parameters. The second approach uses vergence calculations to provide alternative expressions, assuming that the refractive error is located at the corneal plane. Both models are explored for a biometric range typically found in adult human eyes.

Results: The Gaussian and vergence models each instantly balance the input data into a working eye model over the human physiological range and far beyond as demonstrated in various examples. The equations of the Gaussian model are more complicated, while the vergence model experiences more singularities, albeit in trivial or highly unlikely parameter combinations.

Conclusions: The proposed equations form a flexible and robust platform to create eye models from clinical data. Possible applications lie in creating animal eye models or providing a generic reference for real biometric data and the relationships between the ocular dimensions.

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脊椎动物眼睛的通用模型。
目的:提出一套闭式分析方程,根据临床测量的输入参数,一步即可建立一致的眼球模型平衡。这些模型是对文献中现有迭代法的补充:方法:本文介绍了两种不同的方法,均将角膜和晶状体视为等效的薄透镜。第一种称为高斯模型,首先将屈光不正定义为轴向功率(或屈光距离)与全眼功率之间的差值,然后通过填入每个功率的公式进行扩展。由此得出的方程可以将屈光不正、轴向长度、角膜功率、晶状体功率或角膜与晶状体之间的距离作为其他四个参数的函数来求解。第二种方法假设屈光不正位于角膜平面,利用辐辏计算提供替代表达式。这两种模型都是针对成人眼睛的典型生物测量范围进行探索的:结果:高斯模型和辐辏模型都能将输入数据即时平衡为一个工作眼模型,其范围涵盖人体生理范围,甚至远远超出各种示例所演示的范围。高斯模型的方程更为复杂,而辐辏模型则出现更多奇异点,尽管这些奇异点都是微不足道或极不可能出现的参数组合:结论:所提出的方程构成了一个灵活而稳健的平台,可根据临床数据创建眼球模型。可能的应用领域包括创建动物眼球模型,或为真实的生物测量数据和眼球尺寸之间的关系提供通用参考。
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来源期刊
CiteScore
5.10
自引率
13.80%
发文量
135
审稿时长
6-12 weeks
期刊介绍: Ophthalmic & Physiological Optics, first published in 1925, is a leading international interdisciplinary journal that addresses basic and applied questions pertinent to contemporary research in vision science and optometry. OPO publishes original research papers, technical notes, reviews and letters and will interest researchers, educators and clinicians concerned with the development, use and restoration of vision.
期刊最新文献
Refractive development II: Modelling normal and myopic eye growth. What intrinsic factors affect the central corneal thickness? The effect of lens and fitting characteristics upon scleral lens centration. Recommended improvements to the statistical guidelines. Exploring the relationship between 24-2 visual field and widefield optical coherence tomography data across healthy, glaucoma suspect and glaucoma eyes.
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