The Correlation of Fluid Creep with Fluid and Electrolyte Imbalance In Pediatric Intensive Care Unit Dr. Cipto Mangunkusumo National Central Public Hospital.

IF 1.3 Q3 PEDIATRICS Turkish archives of pediatrics Pub Date : 2024-07-01 DOI:10.5152/TurkArchPediatr.2024.23309
Irene Yuniar, Jojor Sihotang, Regina Suriadi, Devina June
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Abstract

Fluid creep, used as a drug diluent can contribute to fluid and electrolyte balance. Fluid creep brings substantial volume and electrolyte load to patients, especially in critically ill children. This study is conducted to evaluate the correlation of fluid creep with fluid and electrolyte balance in critically ill children. This cross-sectional study was conducted in a single tertiary center. We include children aged 1 month- 18 years in the pediatric intensive care unit (PICU). Exclusion criteria were patients receiving renal replacement therapy and plasmapheresis. Fluids and electrolyte intake were recorded at admission and the first 24 hours in the PICU. A total of 64 patients were observed. The sources of fluid intake are 61% from parenteral, 25% from enteral nutrition, and 12% from fluid creep. There were significant correlations between the volume (r = 0.304, P = .015) and electrolyte intake (r = 0.742, P = .035) of fluid creep with daily fluid balance. There is no correlation between fluid creep and electrolyte changes in 24 hours. Fifty-two patients used WFI (81.2%) as a drug diluent. Our study showed that fluid creep constitutes 12% of daily fluid intake. There is a correlation between the volume and electrolyte intake from fluid creep to daily fluid balance, so it is important to include the volume of fluid creep in calculating the fluid balance. Thus, it is recommended to use hypotonic fluid like WFI compared to NaCl 0.9% for drug diluent.

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儿科重症监护室液体蠕变与体液和电解质失衡的相关性 Cipto Mangunkusumo 博士,国立中央公立医院。
作为药物稀释剂使用的液体蠕变可促进体液和电解质平衡。液体蠕变会给患者带来巨大的容量和电解质负荷,尤其是重症儿童。本研究旨在评估液体蠕变与重症儿童体液和电解质平衡的相关性。这项横断面研究在一家三级医疗中心进行。研究对象包括儿科重症监护室(PICU)中 1 个月至 18 岁的儿童。排除标准是正在接受肾脏替代疗法和血浆置换术的患者。记录了入院时和在 PICU 的头 24 小时的液体和电解质摄入量。共观察了 64 名患者。液体摄入量的61%来自肠外营养,25%来自肠内营养,12%来自液体蠕动。液体爬行的体积(r = 0.304,P = .015)和电解质摄入量(r = 0.742,P = .035)与每日液体平衡之间存在明显的相关性。液体爬行与 24 小时内的电解质变化之间没有相关性。52 名患者使用 WFI(81.2%)作为药物稀释剂。我们的研究表明,液体蠕变占每日液体摄入量的 12%。液体蠕变的体积和电解质摄入量与每日液体平衡之间存在相关性,因此在计算液体平衡时必须包括液体蠕变的体积。因此,与 0.9% 氯化钠相比,建议使用 WFI 等低渗液体作为药物稀释剂。
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