How to assess survival prognosis in patients hospitalized for community-acquired pneumonia in 2024?

IF 3.5 3区医学 Q1 CRITICAL CARE MEDICINE Current Opinion in Critical Care Pub Date : 2024-10-01 Epub Date: 2024-07-12 DOI:10.1097/MCC.0000000000001189

Julio A Ramirez, Thomas M File

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Abstract

Purpose of review: Community-acquired pneumonia (CAP) is increasingly recognized as a complex, multisystemic disease with the potential to cause both acute and long-term sequelae, significantly impacting patient mortality rates. In this manuscript, the authors review the current methodologies for assessing mortality risk among CAP patients.

Recent findings: The most common prediction scores for ICU care and short-term mortality include Pneumonia Severity Index (PSI), CURB-65, SMART COP, SCAP, and ATS/IDSA criteria. These models have clinical utility in the prediction of short-term mortality, but they have significant limitations in addressing long-term mortality. For patients who are discharged alive from the hospital, we do not have scores to predict long term mortality.

Summary: The development of an optimal prognostic tool for postacute sequelae of CAP is imperative. Such a tool should identify specific populations at increased risk. Moreover, accurately identifying at-risk populations is essential for their inclusion in clinical trials that evaluate potential therapies designed to improve short and long-term clinical outcomes in patients with CAP.

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如何评估 2024 年社区获得性肺炎住院患者的生存预后？

综述的目的：越来越多的人认识到社区获得性肺炎（CAP）是一种复杂的多系统疾病，有可能引起急性和长期后遗症，严重影响患者的死亡率。在这篇手稿中，作者回顾了目前评估 CAP 患者死亡风险的方法：最常见的 ICU 护理和短期死亡率预测评分包括肺炎严重程度指数 (PSI)、CURB-65、SMART COP、SCAP 和 ATS/IDSA 标准。这些模型在预测短期死亡率方面具有临床实用性，但在处理长期死亡率方面有很大的局限性。对于出院后仍存活的患者，我们还没有预测长期死亡率的评分。这种工具应能识别风险增加的特定人群。此外，准确识别高危人群对于将他们纳入临床试验至关重要，这些临床试验将评估旨在改善 CAP 患者短期和长期临床预后的潜在疗法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current Opinion in Critical Care 医学-危重病医学

CiteScore

5.90

自引率

3.00%

发文量

172

审稿时长

6-12 weeks

期刊介绍： Current Opinion in Critical Care delivers a broad-based perspective on the most recent and most exciting developments in critical care from across the world. Published bimonthly and featuring thirteen key topics – including the respiratory system, neuroscience, trauma and infectious diseases – the journal’s renowned team of guest editors ensure a balanced, expert assessment of the recently published literature in each respective field with insightful editorials and on-the-mark invited reviews.