A first case of Mixta calida bacteremia and meningitis in a 5-week old child.

Infectious diseases (London, England) Pub Date : 2024-11-01 Epub Date: 2024-08-15 DOI:10.1080/23744235.2024.2391022
Stijn Van Hees, Sarah Keulemans, Koen Vanden Driessche, An-Sofie Schoonjans, Truus Goegebuer, Ann Lemmens
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Abstract

Mixta calida, previously known as Pantoea calida, was initially isolated from powdered infant milk in 2010. It falls within the Erwiniaceae family (class: Enterobacterales). While Mixta calida was traditionally regarded as non-pathogenic, we now present a case of Mixta calida bacteraemia and meningitis in a 5-week-old child, successfully treated with cefotaxime. This case, in contrast to prior reports with potential contamination issues, is the first to offer compelling evidence of Mixta calida's pathogenicity in humans.

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首例 5 周大婴儿患卡氏菌菌血症和脑膜炎的病例。
Mixta calida,以前称为 Pantoea calida,最初于 2010 年从婴儿奶粉中分离出来。它属于埃文菌科(Erwiniaceae)(类:肠杆菌属)。尽管传统上认为卡氏变形杆菌不具致病性,但我们现在介绍一例卡氏变形杆菌菌血症和脑膜炎病例,该病例发生在一名 5 周大的儿童身上,使用头孢他啶治疗后获得成功。与之前存在潜在污染问题的报告相比,本病例首次提供了卡氏菌对人类具有致病性的有力证据。
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