Cross section measurements for the production of 49,51Cr and 47Sc from proton irradiation of natural vanadium up to 24 MeV

IF 1.6 3区工程技术 Q3 CHEMISTRY, INORGANIC & NUCLEAR Applied Radiation and Isotopes Pub Date : 2024-08-06 DOI:10.1016/j.apradiso.2024.111469

引用次数: 0

Abstract

Scandium-47 is a promising radionuclide for targeted radiotherapy and is also an elementally matched therapeutic partner to ⁴³Sc and ⁴⁴Sc, which are suitable for Positron Emission Tomography. The predominantly reported routes for the production of ⁴⁷Sc employ expensive enriched titanium or calcium targets to achieve high radionuclidic purity. This study reports measurements of the excitation function of the ^natV(p,x)⁴⁷Sc reaction at proton energies of 18–24 MeV to optimize bombardment parameters for the production of ⁴⁷Sc using this promising approach. The cross-sections reported here demonstrate that irradiation of vanadium targets can produce >99% radionuclidically pure ⁴⁷Sc with a proton energy of 24 MeV, albeit at modest yields.

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质子辐照天然钒至 24 MeV 产生 49、51Cr 和 47Sc 的截面测量。

钪-47是一种很有希望用于靶向放射治疗的放射性核素，也是与43Sc和44Sc元素相匹配的治疗伙伴，适合用于正电子发射断层扫描。据报道，生产 47Sc 的主要途径是采用昂贵的富集钛靶或钙靶，以达到较高的放射性核素纯度。本研究报告测量了质子能量为 18-24 MeV 时 natV(p,x)47Sc 反应的激发函数，以优化使用这种有前途的方法生产 47Sc 的轰击参数。这里报告的截面表明，用 24 MeV 的质子能量辐照钒靶可以产生放射性核素纯度大于 99% 的 47Sc，尽管产量不大。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Applied Radiation and Isotopes 工程技术-核科学技术

CiteScore

3.00

自引率

12.50%

发文量

406

审稿时长

13.5 months

期刊介绍： Applied Radiation and Isotopes provides a high quality medium for the publication of substantial, original and scientific and technological papers on the development and peaceful application of nuclear, radiation and radionuclide techniques in chemistry, physics, biochemistry, biology, medicine, security, engineering and in the earth, planetary and environmental sciences, all including dosimetry. Nuclear techniques are defined in the broadest sense and both experimental and theoretical papers are welcome. They include the development and use of α- and β-particles, X-rays and γ-rays, neutrons and other nuclear particles and radiations from all sources, including radionuclides, synchrotron sources, cyclotrons and reactors and from the natural environment. The journal aims to publish papers with significance to an international audience, containing substantial novelty and scientific impact. The Editors reserve the rights to reject, with or without external review, papers that do not meet these criteria. Papers dealing with radiation processing, i.e., where radiation is used to bring about a biological, chemical or physical change in a material, should be directed to our sister journal Radiation Physics and Chemistry.