An enigmatic combined tumour of oral malignant melanoma and oral squamous cell carcinoma - A rare case report.

Q3 Medicine Journal of Oral and Maxillofacial Pathology Pub Date : 2024-04-01 Epub Date: 2024-07-11 DOI:10.4103/jomfp.jomfp_330_22
S Renuga, N S Sahana, G Suganya, Meghashyama Kulkarni
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Abstract

Combined tumours are those composed of two benign tumours or a benign and malignant tumour or two malignant tumours occurring within the same tumour population. The incidence of combined tumours is very rare. Due to the rarity of these tumours, their biological behaviour remains unlashed. Incisional biopsy of a 48 years old female patient with single, diffuse tumour mass in the oral cavity showed combined tumour or collision tumour of malignant melanoma and squamous cell carcinoma. This was confirmed with immunohistochemistry study. The incidence of combined tumour of malignant melanoma and squamous cell carcinoma in oral cavity is extremely rare. To the best of our knowledge based on the previous literature records, this is the first case report of its kind where there is incidence in the human oral cavity.

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口腔恶性黑色素瘤和口腔鳞状细胞癌的神秘合并肿瘤--罕见病例报告。
合并肿瘤是指由两个良性肿瘤、一个良性肿瘤和一个恶性肿瘤或两个恶性肿瘤组成的同一肿瘤群。合并肿瘤的发病率非常罕见。由于这类肿瘤非常罕见,其生物学行为仍未被揭示。一名 48 岁的女性患者口腔内有单个弥漫性肿瘤肿块,切开活检显示其为恶性黑色素瘤和鳞状细胞癌的合并瘤或碰撞瘤。免疫组化研究证实了这一点。口腔恶性黑色素瘤和鳞状细胞癌合并肿瘤的发病率极为罕见。据我们所知,根据以往的文献记录,这是第一例在人类口腔中发生的同类病例报告。
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来源期刊
Journal of Oral and Maxillofacial Pathology
Journal of Oral and Maxillofacial Pathology Medicine-Otorhinolaryngology
CiteScore
1.40
自引率
0.00%
发文量
115
期刊介绍: The journal of Oral and Maxillofacial Pathology [ISSN:print-(0973-029X, online-1998-393X)] is a tri-annual journal published on behalf of “The Indian Association of Oral and Maxillofacial Pathologists” (IAOMP). The publication of JOMFP was started in the year 1993. The journal publishes papers on a wide spectrum of topics associated with the scope of Oral and Maxillofacial Pathology, also, ensuring scientific merit and quality. It is a comprehensive reading material for the professionals who want to upgrade their diagnostic skills in Oral Diseases; allows exposure to newer topics and methods of research in the Oral-facial Tissues and Pathology. New features allow an open minded thinking and approach to various pathologies. It also encourages authors to showcase quality work done by them and to compile relevant cases which are diagnostically challenging. The Journal takes pride in maintaining the quality of articles and photomicrographs.
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