Chimerism and mosaicism shape our physical constitution and impact medical conditions.

IF 5.1 2区 医学 Q1 HEMATOLOGY British Journal of Haematology Pub Date : 2024-08-20 DOI:10.1111/bjh.19705
Willy Albert Flegel
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引用次数: 0

Abstract

ABO blood group discrepancies in healthy individuals were caused by body-wide chimerism and mosaicism. They can be evaluated with new diagnostic options for disease-related cell clones that are typically associated with mosaicism. The observations raise the attention for sporadic mixed-field observations of any blood group antigen. Commentary on: Dauber et al. Body-wide chimerism and mosaicism are predominant causes of naturally occurring ABO discrepancies. Br J Haematol 2024 (Online ahead of print). doi:10.1111/bjh.19618.

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嵌合体和镶嵌体塑造了我们的体质,并对医疗状况产生影响。
健康人的 ABO 血型差异是由全身嵌合和镶嵌造成的。可以通过与疾病相关的细胞克隆(通常与嵌合相关)的新诊断方案对其进行评估。这些观察结果提高了人们对任何血型抗原零星混合场观察的关注。评论Dauber等:全身嵌合体和嵌合体是自然发生的ABO差异的主要原因。Doi:10.1111/bjh.19618.
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来源期刊
CiteScore
8.60
自引率
4.60%
发文量
565
审稿时长
1 months
期刊介绍: The British Journal of Haematology publishes original research papers in clinical, laboratory and experimental haematology. The Journal also features annotations, reviews, short reports, images in haematology and Letters to the Editor.
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