Exploring the Bioactive Potential of Exotic Fruits from Sri Lanka: A Treasure Trove of Medicinal Properties.

IF 1.6 4区 医学 Q4 BIOCHEMICAL RESEARCH METHODS Combinatorial chemistry & high throughput screening Pub Date : 2024-08-19 DOI:10.2174/0113862073304276240606102447
D M Danuri Savindi Dissanayake, I G Sahasra Heshani, Sadhana Hassan, Anchala I Kuruppu
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Abstract

Tropical fruits are often studied to determine their content of bioactive compounds that contain health-enhancing properties and are often identified to hold a rich nutritional composition. Their bioactive compounds are classified through their phenolic, flavonoid, and antioxidant properties, while some tropical fruits are known to have other properties such as anticancer and anti-inflammatory activity. Sri Lanka is an island with abundant resources. One such resource is exotic fruits. Exotic fruits are known as edible fruits, which are not necessarily native but consist of a unique flavor profile, fragrance, shape, or appearance. Exotic fruits are usually consumed on their own or consumed as beverages, pickles, jams, salads, and desserts. The market-friendly tropical fruits in Sri Lanka include a vast number, and some of them are mango, Ceylon olives, durian, jackfruit, rambutan, soursop, passion fruit, and star fruit. These fruits contribute to the rice culinary heritage of Sri Lanka, and most of them are exported worldwide. At present, the traditional medicine system is quite popular among the public due to its less toxic nature and easy access. This review is aimed at evaluating the antioxidant, cytotoxic, anticancer, and anti-inflammatory properties of eight selected exotic fruits mentioned above and their traditional usage, which is based on the literature of various scientific studies conducted on these tropical fruits.

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探索斯里兰卡外来水果的生物活性潜力:药用价值的宝库。
人们经常研究热带水果,以确定其生物活性化合物的含量,这些化合物具有增进健康的特性,而且经常被认定含有丰富的营养成分。热带水果的生物活性化合物可根据其酚类、类黄酮和抗氧化特性进行分类,有些热带水果还具有其他特性,如抗癌和抗炎活性。斯里兰卡是一个资源丰富的岛屿。其中一种资源就是奇特水果。异国水果被称为可食用水果,不一定是本地水果,但具有独特的风味、香味、形状或外观。外来水果通常单独食用或作为饮料、腌菜、果酱、沙拉和甜点食用。斯里兰卡市场上的热带水果种类繁多,其中包括芒果、锡兰橄榄、榴莲、菠萝蜜、红毛丹、酸果、百香果和杨桃。这些水果为斯里兰卡的稻米烹饪遗产做出了贡献,其中大部分出口到世界各地。目前,传统医药系统因其毒性较低、易于获取而颇受公众欢迎。本综述旨在评估上述八种精选外来水果的抗氧化、细胞毒性、抗癌和消炎特性及其传统用法,其依据是对这些热带水果进行的各种科学研究文献。
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来源期刊
CiteScore
3.10
自引率
5.60%
发文量
327
审稿时长
7.5 months
期刊介绍: Combinatorial Chemistry & High Throughput Screening (CCHTS) publishes full length original research articles and reviews/mini-reviews dealing with various topics related to chemical biology (High Throughput Screening, Combinatorial Chemistry, Chemoinformatics, Laboratory Automation and Compound management) in advancing drug discovery research. Original research articles and reviews in the following areas are of special interest to the readers of this journal: Target identification and validation Assay design, development, miniaturization and comparison High throughput/high content/in silico screening and associated technologies Label-free detection technologies and applications Stem cell technologies Biomarkers ADMET/PK/PD methodologies and screening Probe discovery and development, hit to lead optimization Combinatorial chemistry (e.g. small molecules, peptide, nucleic acid or phage display libraries) Chemical library design and chemical diversity Chemo/bio-informatics, data mining Compound management Pharmacognosy Natural Products Research (Chemistry, Biology and Pharmacology of Natural Products) Natural Product Analytical Studies Bipharmaceutical studies of Natural products Drug repurposing Data management and statistical analysis Laboratory automation, robotics, microfluidics, signal detection technologies Current & Future Institutional Research Profile Technology transfer, legal and licensing issues Patents.
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