Association of redundant foreskin with sexual dysfunction: a cross-sectional study from 5700 participants.

Yuan-Qi Zhao, Nian Li, Xiao-Hua Jiang, Yang-Yang Wan, Bo Xu, Xue-Chun Hu, Yi-Fu Hou, Ji-Yan Li, Shun Bai
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Abstract

A previous study showed that the length of the foreskin plays a role in the risk of sexually transmitted infections and chronic prostatitis, which can lead to poor quality of sexual life. Here, the association between foreskin length and sexual dysfunction was evaluated. A total of 5700 participants were recruited from the andrology clinic at The First Affiliated Hospital of University of Science and Technology of China (Hefei, China). Clinical characteristics, including foreskin length, were collected, and sexual function was assessed by the International Index of Erectile Function-5 (IIEF-5) and Premature Ejaculation Diagnostic Tool (PEDT) questionnaires. Men with sexual dysfunction were more likely to have redundant foreskin than men without sexual dysfunction. Among the 2721 erectile dysfunction (ED) patients and 1064 premature ejaculation (PE) patients, 301 (11.1%) ED patients and 135 (12.7%) PE patients had redundant foreskin, respectively. Men in the PE group were more likely to have redundant foreskin than men in the non-PE group (P = 0.004). Logistic regression analyses revealed that the presence of redundant foreskin was associated with increased odds of moderate/severe ED (adjusted odds ratio [aOR] = 1.31, adjusted P = 0.04), moderate PE (aOR = 1.38, adjusted P = 0.02), and probable PE (aOR = 1.37, adjusted P = 0.03) after adjusting for confounding variables. Our study revealed a positive correlation between the presence of redundant foreskin and the risk of sexual dysfunction, especially in PE patients. Assessment of the length of the foreskin during routine clinical diagnosis may provide information for patients with sexual dysfunction.

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多余包皮与性功能障碍的关系:对 5700 名参与者进行的横断面研究。
先前的一项研究表明,包皮的长度对性传播感染和慢性前列腺炎的风险有一定影响,会导致性生活质量低下。本研究评估了包皮长度与性功能障碍之间的关系。中国科学技术大学第一附属医院(中国合肥)泌尿外科门诊共招募了 5700 名参与者。研究人员收集了包括包皮长度在内的临床特征,并通过国际勃起功能指数-5(IIEF-5)和早泄诊断工具(PEDT)问卷评估了性功能。与没有性功能障碍的男性相比,有性功能障碍的男性更有可能有多余的包皮。在2721名勃起功能障碍(ED)患者和1064名早泄(PE)患者中,分别有301名(11.1%)ED患者和135名(12.7%)PE患者有多余包皮。PE组男性比非PE组男性更容易出现包皮过长(P = 0.004)。逻辑回归分析显示,在调整了混杂变量后,存在多余包皮与中度/重度ED(调整后的几率比[aOR] = 1.31,调整后的P = 0.04)、中度PE(aOR = 1.38,调整后的P = 0.02)和可能PE(aOR = 1.37,调整后的P = 0.03)的几率增加有关。我们的研究显示,多余包皮的存在与性功能障碍的风险呈正相关,尤其是在 PE 患者中。在常规临床诊断中评估包皮长度可为性功能障碍患者提供信息。
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