Unraveling the spectrum of airway complications following lung transplantation: a comprehensive overview.

IF 1.8 4区 医学 Q3 TRANSPLANTATION Current Opinion in Organ Transplantation Pub Date : 2024-10-01 Epub Date: 2024-08-21 DOI:10.1097/MOT.0000000000001162
Zehra Dhanani, Rachel Criner, Gerard J Criner
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Abstract

Purpose of review: This review delves into the intricate landscape of airway complications post lung transplantation. With the rising prevalence of end-stage lung disease and the increasing number of lung transplantation worldwide, understanding and effectively managing airway complications are crucial. Given the nuanced nature of these complications and the array of treatment options available, this review aims to provide a comprehensive overview of how to identify, classify, mitigate risk factors for, and manage these complications.

Recent findings: Several donor, recipient, and surgical risk factors are associated with the increased risk of airway complications. In managing these complications, bronchoscopic interventions, notably balloon dilation and stenting, are pivotal. Although self-expanding metallic stents offer versatility, silicone stents are preferred in certain scenarios for their durability. Emerging techniques such as biodegradable stents and advancing imaging modalities show promise in mitigating complications and improving outcomes.

Summary: These findings underscore the significance of a multidisciplinary approach and personalized treatment algorithms in managing airway complications post lung transplantation. By elucidating specific indications and complications of treatment modalities, this review serves as a valuable resource for optimally managing airway complications. Ongoing research into novel interventions holds promise for further enhancing outcomes in this challenging clinical setting.

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解读肺移植术后气道并发症:全面概述。
综述的目的:这篇综述深入探讨了肺移植术后气道并发症的复杂情况。随着终末期肺病发病率的上升和全球肺移植数量的增加,了解并有效控制气道并发症至关重要。鉴于这些并发症的细微差别和一系列可用的治疗方案,本综述旨在全面概述如何识别、分类、减轻风险因素和管理这些并发症:一些供体、受体和手术风险因素与气道并发症风险的增加有关。在处理这些并发症时,支气管镜介入治疗,特别是球囊扩张和支架植入术至关重要。虽然自膨胀金属支架具有多功能性,但在某些情况下,硅胶支架因其耐用性而成为首选。生物可降解支架和先进的成像模式等新兴技术有望减轻并发症并改善预后。总结:这些研究结果强调了多学科方法和个性化治疗算法在控制肺移植术后气道并发症方面的重要性。本综述阐明了各种治疗方法的具体适应症和并发症,是优化气道并发症管理的宝贵资源。对新型干预措施的持续研究有望进一步提高这一具有挑战性的临床环境的治疗效果。
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来源期刊
CiteScore
4.10
自引率
4.50%
发文量
124
审稿时长
6-12 weeks
期刊介绍: ​​​​​​Current Opinion in Organ Transplantation is an indispensable resource featuring key, up-to-date and important advances in the field from around the world. Led by renowned guest editors for each section, every bimonthly issue of Current Opinion in Organ Transplantation delivers a fresh insight into topics such as stem cell transplantation, immunosuppression, tolerance induction and organ preservation and procurement. With 18 sections in total, the journal provides a convenient and thorough review of the field and will be of interest to researchers, surgeons and other healthcare professionals alike.
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