Pseudoglutamicibacter cumminsii in polymicrobial osteomyelitis of the tibia in a female patient - a case report.

IF 1.7 Q3 INFECTIOUS DISEASES GERMS Pub Date : 2024-03-31 eCollection Date: 2024-03-01 DOI:10.18683/germs.2024.1421
Petros Ioannou, Sofia Maraki, Emmanuel Velivasakis, Diamantis P Kofteridis
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Abstract

Introduction: Pseudoglutamicibacter cumminsii (formerly Arthrobacter cumminsii) is a microorganism rarely reported as a cause of infection. It is a Gram-positive, non-motile, and non-spore-forming bacterium belonging to the Micrococcaceae family. It is known for its environmental ubiquity, being frequently found in soil, water, and other ecological niches.

Case report: A 39-year-old woman with a history of glucose-6-phosphate dehydrogenase deficiency and multiple surgeries at the left lower extremity for osteomyelitis at the left tibia presented with a relapse of chronic osteomyelitis of the left tibia. She underwent surgical debridement, and cultures grew Enterococcus faecalis, Pseudomonas aeruginosa, Klebsiella oxytoca, Proteus mirabilis, and Pseudoglutamicibacter cumminsii, according to identification with matrix-assisted laser desorption/ionization-time of flight mass spectrometry. Targeted antimicrobial treatment with ciprofloxacin and amoxicillin-clavulanate for six weeks led to patient recovery.

Conclusions: Accurate identification by advanced diagnostic techniques is essential for effectively managing rare pathogens. Further research and reporting of cases are needed to understand better the epidemiology, pathogenesis, optimal treatment, and improved clinical outcomes associated with P. cumminsii infections.

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一名女性患者胫骨多菌性骨髓炎中的累积假谷氨酸杆菌--病例报告。
导言:积膜假谷氨酸杆菌(原积膜节杆菌)是一种极少被报道可导致感染的微生物。它是一种革兰氏阳性细菌,不运动,不形成孢子,属于微球菌科。它在环境中无处不在,经常出现在土壤、水和其他生态位中:病例报告:一名 39 岁的女性,患有葡萄糖-6-磷酸脱氢酶缺乏症,曾因左胫骨骨髓炎在左下肢做过多次手术,后来左胫骨慢性骨髓炎复发。她接受了手术清创,根据基质辅助激光解吸/电离飞行时间质谱鉴定,培养出了粪肠球菌、铜绿假单胞菌、克雷伯菌、奇异变形杆菌和积假谷氨酸杆菌。使用环丙沙星和阿莫西林-克拉维酸进行为期六周的针对性抗菌治疗后,患者痊愈:通过先进的诊断技术进行准确鉴定对于有效处理罕见病原体至关重要。我们需要进一步研究和报告病例,以更好地了解积雪蟠菌感染的流行病学、发病机制、最佳治疗方法和临床疗效。
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来源期刊
GERMS
GERMS INFECTIOUS DISEASES-
CiteScore
2.80
自引率
5.00%
发文量
36
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