Hearing, balance, and imaging assessment in adolescent Menière's disease: A retrospective analysis

IF 1.6 4区医学 Q2 OTORHINOLARYNGOLOGY Laryngoscope Investigative Otolaryngology Pub Date : 2024-08-21 DOI:10.1002/lio2.1313

Xiaofei Li MD, PhD, Xiaoyi Li MD, Yafeng Lyu MD, PhD, Huirong Jian MD, Yawei Li MD, Jing Wang MD, Wenjuan Li MD, Ruyan Wang MD, Yinghui Hu MD, Zhaomin Fan, Haibo Wang MD, Daogong Zhang MD, PhD

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Abstract

Objective

To retrospectively analyze clinical features in adolescent Menière's disease (MD).

Methods

The medical records of adolescents with MD (11–17 years old) from May 2014 to March 2023 in Shandong Provincial ENT Hospital were retrospectively analyzed, including clinical features, a battery of auditory and vestibular function tests, sensory organization test, and imaging assessments. Patients with recurrent vertigo of childhood (RVC) were as controls.

Results

Compared with RVC, adolescent MD showed higher pure tone average threshold (p < .001), lower speech discrimination score (p = .014), and lower otoacoustic emission pass rates (p = .005). Adolescents with MD exhibited significant reduction in equilibrium score (Conditions 1, 5, and 6; p1 = .035; p5 = .033; p6 = .003), composite sensory score (p = .014), and vestibular sensory score (p = .029). Adolescents with bilateral MD exhibited worse performance in equilibrium score and strategy score compared to adolescents with unilateral MD. For the affected ear, the more severe endolymphatic hydrops detected by gadolinium-enhanced magnetic resonance imaging, the higher the auditory brainstem response threshold (r = .850, p = .007), and the lower the otoacoustic emission pass rate (r = −.976, p < .001).

Conclusion

Adolescent MD has similar vestibular information inputs with that of RVC, but the ability for the nerve center to use these clues to maintain balance is worse in adolescents with MD. There were potential differences in vestibular weights in adolescents with unilateral and bilateral MD, also potential effects on vision and proprioception.

Level of Evidence

Level 4.

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青少年梅尼埃病的听力、平衡和影像评估：回顾性分析。

目的：回顾性分析青少年梅尼埃病（MD）的临床特征：回顾性分析青少年梅尼埃病（MD）的临床特征：方法：回顾性分析山东省耳鼻喉科医院2014年5月至2023年3月收治的梅尼埃病青少年患者（11-17岁）的病历，包括临床特征、听觉和前庭功能检查、感觉组织检查和影像学评估。儿童复发性眩晕（RVC）患者为对照组：结果：与 RVC 相比，青少年 MD 显示出更高的纯音平均阈值（p p = .014）和更低的耳声发射通过率（p = .005）。患有 MD 的青少年在平衡得分（条件 1、5 和 6；p1 = .035；p5 = .033；p6 = .003）、综合感觉得分（p = .014）和前庭感觉得分（p = .029）方面均有显著下降。与单侧 MD 青少年相比，双侧 MD 青少年在平衡得分和策略得分方面表现较差。就患耳而言，钆增强磁共振成像检测到的内淋巴水肿越严重，听性脑干反应阈值就越高（r = .850，p = .007），耳声发射通过率就越低（r = -.976，p 结论：青少年 MD 与前庭感觉相似：青少年 MD 患者的前庭信息输入与 RVC 患者相似，但青少年 MD 患者的神经中枢利用这些线索保持平衡的能力较差。单侧和双侧 MD 青少年的前庭重量存在潜在差异，对视觉和本体感觉也有潜在影响：证据等级：4级。

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