Type and morphology affect the success rate of bronchoscopy for postintubation tracheal stenosis

IF 1.6 4区 医学 Q2 OTORHINOLARYNGOLOGY Laryngoscope Investigative Otolaryngology Pub Date : 2024-08-21 DOI:10.1002/lio2.70002
Mingyuan Yang MS, Hong Li BS, Yunzhi Zhou MS, Huafeng Wei MD, Qinghao Cheng MD
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Abstract

Objective

With advancements in respiratory interventional techniques, bronchoscopic intervention technology has emerged as a viable approach for managing postintubation tracheal stenosis (PITS). However, there was a paucity of research investigating the potential impact of stenosis characteristics and morphology (such as stenosis degree, length, type, and morphology) on bronchoscopic intervention treatment prognosis for PITS patients. This study was to assess the impact of various preoperative stenosis characteristic factors on the bronchoscopic cure rate among patients.

Methods

This is a retrospective study analyzing the medical records of patients with PITS who received bronchoscopic intervention at the tertiary interventional pulmonology center.

Results

Among the cases, 115 individuals achieved a in a success rate of 79.86% for bronchoscopic intervention therapy and were assigned to Group S. On the other hand, 29 cases required surgical intervention, accounting for a surgical treatment rate of 20.14% and were assigned to Group F. The stenosis in the Group F predominantly exhibited irregular shapes with scar granulation accompanied by tracheal chondromalacia collapse. Patients in group S experienced fewer total procedures, rigid bronchoscopy treatment, intraoperative hypoxemia, needed emergency re-bronchoscopy in 24 h and transferred to ICU postoperatively. Patients with pure scar and granuloma, the rate of bronchoscopic success cure was higher than patients with scar granulation accompanied by tracheal chondromalacia (odds ratio: 8.208; 95% confidence interval: 2.755–24.459), and regular stenosis morphology was associated with a higher bronchoscopic success cure rate (odds ratio: 9.463; 95% confidence interval: 3.128–28.623).

Conclusion

Irregular airway stenosis, chondromalacia or airway collapse are key factors affecting the success rate of bronchoscopic treatment for post-intubation tracheal stenosis.

Level of evidence: 4 (historically controlled studies).

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类型和形态会影响气管镜检查插管后气管狭窄的成功率。
目的:随着呼吸介入技术的发展,支气管镜介入技术已成为治疗插管后气管狭窄(PITS)的一种可行方法。然而,有关狭窄特征和形态(如狭窄程度、长度、类型和形态)对气管镜介入治疗 PITS 患者预后的潜在影响的研究却很少。本研究旨在评估各种术前狭窄特征因素对患者支气管镜治愈率的影响:这是一项回顾性研究,分析了在三级介入肺科中心接受支气管镜介入治疗的 PITS 患者的病历:F组患者的气管狭窄主要表现为不规则形状,瘢痕肉芽增生,伴有气管软骨塌陷。S 组患者经历的总手术次数、硬质支气管镜治疗次数、术中低氧血症、需要在 24 小时内再次进行急诊支气管镜检查以及术后转入重症监护室的次数均较少。纯瘢痕肉芽肿患者的支气管镜下成功治愈率高于瘢痕肉芽肿伴气管软骨瘤患者(几率比:8.208;95% 置信区间:2.755-24.459),且气道狭窄形态规则与较高的支气管镜下成功治愈率相关(几率比:9.463;95% 置信区间:3.128-28.623):结论:不规则气道狭窄、软骨软化或气道塌陷是影响气管插管后气管狭窄支气管镜治疗成功率的关键因素。证据等级:4(历史对照研究)。
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3.00
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0.00%
发文量
245
审稿时长
11 weeks
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