Durable left ventricular assist devices as a bridge to transplantation: what to expect along the way?

Andrea Fernandez Valledor, Cathrine M Moeller, Gal Rubinstein, Daniel Oren, Salwa Rahman, Julia Baranowska, Changhee Lee, Daniel Lorenzatti, Francesca Maria Righini, Dor Lotan, Gabriel T Sayer, Nir Uriel
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Abstract

Introduction: The scarcity of donors coupled with the improvements in left ventricular assist devices (LVAD) technology has led to the use of LVAD as a bridge to transplantation (BTT).

Areas covered: The authors provide an overview of the current status of LVAD BTT implantation with special focus ranging from patient selection and pre-implantation optimization to post-transplant outcomes.

Expert opinion: The United Network for Organ Sharing 2018 policy amendment resulted in a significant reduction in the number of LVADs used for BTT in the US. To overcome this issue, modifications in the US allocation policy to consider factors such as days on device support, age, and type of complications may be necessary to potentially increase implantation rates.

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作为移植桥梁的耐用左心室辅助装置:一路上有哪些期待?
简介:捐献者的稀缺和左心室辅助装置(LVAD)技术的进步促使人们使用LVAD作为移植(BTT)的桥梁:作者概述了LVAD BTT植入的现状,特别关注从患者选择、植入前优化到移植后预后等方面:器官共享联合网络2018年政策修正案导致美国用于BTT的LVAD数量大幅减少。为了克服这一问题,可能有必要修改美国的分配政策,以考虑设备支持天数、年龄和并发症类型等因素,从而有可能提高植入率。
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