Budesonide Orodispersible Tablet for the Treatment of Refractory Esophageal Lichen Planus.

IF 0.6 Q4 GASTROENTEROLOGY & HEPATOLOGY ACG Case Reports Journal Pub Date : 2024-08-22 eCollection Date: 2024-08-01 DOI:10.14309/crj.0000000000001460
Thomas Skinner, Sharron Liang, Santosh Sanagapalli
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Abstract

Esophageal lichen planus is an uncommon but highly morbid condition where effective treatments are limited. Diagnosis may be challenging and requires a high degree of clinical suspicion considering endoscopic, histopathological, esophageal, and extraesophageal manifestations. We describe a severe case of esophageal lichen planus and recurrent esophageal stricture that was refractory to acid suppression, local and systemic steroid formulations, and dilatation. We present the first reported use of budesonide orodispersible tablet for this condition, including the excellent clinical, endoscopic, and histopathological response.

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用于治疗难治性食管扁平苔藓的布地奈德乳油分散片
食管扁平苔藓是一种不常见但发病率很高的疾病,有效的治疗方法有限。诊断可能具有挑战性,需要考虑内镜、组织病理学、食管和食管外的表现,临床上需要高度怀疑。我们描述了一例严重的食管扁平苔藓和复发性食管狭窄病例,该病例对抑酸、局部和全身类固醇制剂以及扩张术均无效。我们首次报道了布地奈德口崩片剂用于该病症的治疗,包括出色的临床、内窥镜和组织病理学反应。
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来源期刊
ACG Case Reports Journal
ACG Case Reports Journal GASTROENTEROLOGY & HEPATOLOGY-
自引率
14.30%
发文量
170
审稿时长
12 weeks
期刊介绍: ACG Case Reports Journal is a peer-reviewed, open-access publication that provides GI and hepatology fellows, private practice clinicians, and other healthcare providers an opportunity to share interesting case reports with their peers and with leaders in the field. ACG Case Reports Journal publishes case reports, images, videos and letters to the editor in all topics of gastroenterology and hepatology, including: Biliary Colon Endoscopy Esophagus Functional Bowel Disorders Inflammatory Bowel Disease Liver Nutrition and Obesity Pancreas Pathology Pediatric Small Bowel Stomach.
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