Mutual Effects of Coincident Chronic Renal Failure and Chronic Obstructive Pulmonary Disease.

Q3 Medicine Tanaffos Pub Date : 2023-04-01

Fatemeh Yassari, Seyed Mehran Marashian, Abolfazl Ghasemi Monfared, Somayeh Lookzadeh

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Abstract

Background: The current study tried to assess the effects of CKD on the severity and outcome of COPD in a population of patients who referred to our tertiary center in Tehran through a 3-year time section.

Materials and methods: Through a retrospective cross-sectional design, the current study tried to assess the effects of chronic kidney disease (CKD) on the health situation and some spirometric and para-clinical parameters as well as their outcomes in patients who had been hospitalized for COPD. The participants had already COPD and we separate them into two groups with or without CKD.

Results: Regarding the outcome of hospitalizations, 94% of the COPD and 77.9% of the COPD+CKD group were discharged in good health condition while 6% and 22.1% deceased, respectively. This shows significantly higher death rate in the latter group and the findings obtained the odds ratio of 4.5 for CKD to raise this rate.

Conclusion: The current study could suggest an absolute relationship between CKD and COPD in terms of respiratory and blood parameters as well as the mutual effects of the diseases on the outcome of each.

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并发慢性肾功能衰竭和慢性阻塞性肺病的相互影响。

研究背景本研究试图评估慢性肾脏病对慢性阻塞性肺病严重程度和预后的影响：本研究采用回顾性横断面设计，试图评估慢性肾脏病（CKD）对慢性阻塞性肺疾病住院患者的健康状况、一些肺活量和辅助临床参数及其预后的影响。参与者均已患有慢性阻塞性肺病，我们将他们分为有慢性肾脏病和无慢性肾脏病两组：关于住院治疗的结果，慢性阻塞性肺病组和慢性阻塞性肺病+慢性阻塞性肺病组分别有 94% 和 77.9% 的患者出院时健康状况良好，分别有 6% 和 22.1% 的患者死亡。这表明慢性阻塞性肺病组的死亡率明显高于慢性阻塞性肺病+慢性阻塞性肺病组：目前的研究表明，慢性肾脏病和慢性阻塞性肺病在呼吸和血液参数方面存在绝对关系，而且这两种疾病对各自的预后都有相互影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Tanaffos Medicine-Critical Care and Intensive Care Medicine

CiteScore

1.10

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0.00%

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