Doing better on dialysis: Open pilot outcomes of a technology-assisted, entertaining, CBT-based depression treatment for people with end stage kidney disease at a dialysis clinic

Peter Felsman , Addie Weaver , Jonathan Segal , Marni Jacobson , Caroline Landry , Karen Crampton , Jamila Abdur-Rahman , Andrea DeKam , Tracey Doss-Simmons , Joseph Himle
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Abstract

This pilot study examines change in dialysis patients’ depressive and anxiety symptoms after participation in a technology-assisted, entertaining, 8-session CBT program called Doing Better on Dialysis (DBD). A one-group pre-/post- test design assessed symptom change over time (baseline, post-treatment, three-month follow-up). Nonparametric tests, including Wilcoxon signed rank tests and Friedman’s related samples tests, were used to assess outcomes. Participants experienced a statistically and clinically significant decrease in depressive symptoms between baseline (Median = 12.00, n = 8) and post-treatment (Median = 5.00, n = 7) assessments, as measured by the PHQ-9 (z = −2.12, p = .034). Similar, though non-significant, patterns were observed for anxiety, via the GAD-7. Friedman’s tests revealed a significant overall pattern of difference on the PHQ-9 across all three timepoints in the expected direction. This pilot study provides preliminary support for DBD as a depression treatment for end stage kidney disease patients.

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在透析中做得更好:在透析诊所为终末期肾病患者提供以技术辅助、娱乐和 CBT 为基础的抑郁治疗的公开试点结果
这项试验性研究探讨了透析患者在参加一项名为 "透析中做得更好"(DBD)的技术辅助、娱乐性、共 8 课时的 CBT 项目后抑郁和焦虑症状的变化。采用单组前/后测试设计,评估症状随时间(基线、治疗后、三个月随访)的变化。评估结果采用非参数检验,包括 Wilcoxon 符号秩检验和弗里德曼相关样本检验。根据 PHQ-9 测量(z = -2.12,p = .034),在基线(中位数 = 12.00,n = 8)和治疗后(中位数 = 5.00,n = 7)评估之间,参与者的抑郁症状出现了统计学和临床意义上的显著下降。通过 GAD-7 也观察到了类似的焦虑模式,但并不显著。弗里德曼检验显示,在所有三个时间点上,PHQ-9 的总体差异模式与预期方向一致。这项试点研究为将 DBD 作为末期肾病患者的抑郁症治疗方法提供了初步支持。
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来源期刊
Journal of Behavioral and Cognitive Therapy
Journal of Behavioral and Cognitive Therapy Psychology-Clinical Psychology
CiteScore
3.30
自引率
0.00%
发文量
38
审稿时长
60 days
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