An Interprofessional Team for Disease-Modifying Therapy in Alzheimer Disease Implementation.

IF 2.3 Q3 CLINICAL NEUROLOGY Neurology. Clinical practice Pub Date : 2024-12-01 Epub Date: 2024-08-16 DOI:10.1212/CPJ.0000000000200346
Katherine W Turk, Mark D Knobel, Alexandra Nothern, Garrett Friedman, Hannah Noah, Brendan Campbell, Diana C Anderson, Andreas Charidimou, Andrew Mills, Vanessa Coronel, Nacha Pierre, Beverly V Reynolds, Caroline Wagner, Leanne M Varga, John Roefaro, Laura Triantafylidis, Andrew E Budson
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Abstract

Background: Lecanemab and other new amyloid-targeting immunotherapies for Alzheimer disease show notable promise but may also pose significant risk for patients.

Recent findings: To facilitate the implementation and monitoring of lecanemab infusions at our tertiary medical center, we convened an interprofessional team. The team created a number of resources including patient handouts and medical documentation templates as well as systems and processes that are likely to be useful to other clinical care settings and centers.

Implications for practice: It is our intent to widely share the resources and processes developed.

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跨专业团队实施阿尔茨海默病的疾病调节疗法。
背景:来卡尼单抗和其他治疗阿尔茨海默病的新型淀粉样蛋白靶向免疫疗法显示出显著的前景,但也可能给患者带来巨大风险:为了便于在我们的三级医疗中心实施和监测莱卡单抗输注,我们召集了一个跨专业团队。该团队创建了一系列资源,包括患者手册、医疗文件模板以及可能对其他临床护理机构和中心有用的系统和流程:我们打算广泛分享所开发的资源和流程。
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来源期刊
Neurology. Clinical practice
Neurology. Clinical practice CLINICAL NEUROLOGY-
CiteScore
4.00
自引率
0.00%
发文量
77
期刊介绍: Neurology® Genetics is an online open access journal publishing peer-reviewed reports in the field of neurogenetics. The journal publishes original articles in all areas of neurogenetics including rare and common genetic variations, genotype-phenotype correlations, outlier phenotypes as a result of mutations in known disease genes, and genetic variations with a putative link to diseases. Articles include studies reporting on genetic disease risk, pharmacogenomics, and results of gene-based clinical trials (viral, ASO, etc.). Genetically engineered model systems are not a primary focus of Neurology® Genetics, but studies using model systems for treatment trials, including well-powered studies reporting negative results, are welcome.
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