Assessing the potential of artificial intelligence to enhance colonoscopy adenoma detection in clinical practice: a prospective observational trial.

IF 2.1 Q3 GASTROENTEROLOGY & HEPATOLOGY Clinical Endoscopy Pub Date : 2024-08-23 DOI:10.5946/ce.2024.038
Søren Nicolaj Rønborg, Suresh Ujjal, Rasmus Kroijer, Magnus Ploug
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Abstract

Background/aim: This study aimed to evaluate the effectiveness of the GI Genius (Medtronic) module in clinical practice, focusing on the adenoma detection rate (ADR) during colonoscopy. Computer-aided polyp detection (CADe) systems using artificial intelligence have been shown to improve adenoma detection in controlled trials. However, the effectiveness of these systems in clinical practice has recently been questioned.

Methods: This single-center prospective observational study was conducted at the University Hospital of Southern Denmark and included all individuals referred for colonoscopy between November 2020 and January 2021. The primary outcome was ADR, comparing patients examined with CADe to those examined without it. The selection of patients to be examined with the CADe module was completely random.

Results: A total of 502 patients were analyzed (318 in the control group and 184 in the CADe group). The overall ADR was 32.1% with a slight increase in the CADe group (34.7% vs. 30.5%). Multivariable analysis showed a very modest and statistically insignificant increase in ADR (risk ratio, 1.12; 95% confidence interval, 0.88-1.43).

Conclusions: The use of CADe in clinical practice did not increase ADR with statistical significance when compared to colonoscopy without CADe. These findings suggest that the impact of CADe systems in everyday clinical practice are modest.

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评估人工智能在临床实践中加强结肠镜腺瘤检测的潜力:一项前瞻性观察试验。
背景/目的:本研究旨在评估 GI Genius(美敦力)模块在临床实践中的有效性,重点是结肠镜检查期间的腺瘤检出率(ADR)。在对照试验中,使用人工智能的计算机辅助息肉检测(CADe)系统已被证明能提高腺瘤检测率。然而,这些系统在临床实践中的有效性最近受到了质疑:这项单中心前瞻性观察研究在南丹麦大学医院进行,纳入了 2020 年 11 月至 2021 年 1 月期间所有转诊接受结肠镜检查的患者。主要研究结果是ADR,将使用CADe检查的患者与不使用CADe检查的患者进行比较。使用 CADe 模块检查患者的选择完全随机:共分析了 502 名患者(对照组 318 人,CADe 组 184 人)。总体 ADR 为 32.1%,CADe 组略有增加(34.7% 对 30.5%)。多变量分析表明,ADR 的增加幅度很小,在统计学上并不显著(风险比为 1.12;95% 置信区间为 0.88-1.43):结论:与不使用 CADe 的结肠镜检查相比,在临床实践中使用 CADe 并未增加 ADR,且无统计学意义。这些研究结果表明,在日常临床实践中使用 CADe 系统的影响不大。
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来源期刊
Clinical Endoscopy
Clinical Endoscopy GASTROENTEROLOGY & HEPATOLOGY-
CiteScore
4.40
自引率
8.00%
发文量
95
审稿时长
26 weeks
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