Sparing versus Removal of Epiretinal Proliferation in the Surgical Repair of Full-thickness Macular Holes.

IF 2.3 2区医学 Q2 OPHTHALMOLOGY Retina-The Journal of Retinal and Vitreous Diseases Pub Date : 2024-08-23 DOI:10.1097/IAE.0000000000004261

Masaki Fukushima, Kotaro Tsuboi, Ryota Akai, Yuichiro Ishida, Shunji Kusaka, Motohiro Kamei, Atsushi Hayashi, Taku Wakabayashi

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Abstract

Purpose: To evaluate the efficacy of vitrectomy with epiretinal proliferation (EP) sparing for full-thickness macular hole (FTMH) accompanied by EP.

Methods: A multicenter, retrospective study. Eyes were divided into two groups: the sparing group (Group S) included eyes in which the EP around the hole was peeled and preserved, whereas the removal group (Group R) included eyes in which the EP was partially or completely removed. The internal limiting membrane was peeling in all eyes.

Results: Forty-six eyes were included. Twenty-five eyes were in Group S, and 21 eyes were in Group R, with no difference in preoperative best-corrected visual acuity (BCVA) (P = 0.96). After primary surgery, MHs were closed in all eyes, and there were no complications in either group. Postoperative 12-month BCVA significantly improved in both groups (both P < 0.01), while Group S had better 12-month BCVA than Group R (P = 0.016). In the multivariable analysis, EP sparing was associated with better BCVA at 12 months (P = 0.006) after accounting for the minimal macular hole size and preoperative BCVA.

Conclusions: EP sparing and removal were both safe and effective techniques, while EP sparing may provide a favorable outcome for eyes with FTMH and EP.

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全厚黄斑孔手术修复中保留与去除视网膜外增殖的比较

目的：评估玻璃体切割同时保留视网膜上皮增生（EP）治疗伴有EP的全厚黄斑孔（FTMH）的疗效：多中心回顾性研究。将眼球分为两组：保留组（S 组）包括剥离并保留孔周围 EP 的眼球，而切除组（R 组）包括部分或完全切除 EP 的眼球。结果：结果：共纳入 46 只眼睛。S组25只眼，R组21只眼，术前最佳矫正视力（BCVA）无差异（P = 0.96）。初级手术后，所有眼球的 MH 均闭合，两组均未出现并发症。两组患者术后 12 个月的 BCVA 均有明显改善（P 均 < 0.01），而 S 组患者 12 个月的 BCVA 好于 R 组（P = 0.016）。在多变量分析中，在考虑了最小黄斑孔大小和术前 BCVA 后，EP 疏除与 12 个月的 BCVA 改善相关（P = 0.006）：结论：EP保留和切除都是安全有效的技术，而EP保留可为患有FTMH和EP的眼球提供良好的预后。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Retina-The Journal of Retinal and Vitreous Diseases 医学-眼科学

CiteScore

5.70

自引率

9.10%

发文量

554

审稿时长

3-6 weeks

期刊介绍： RETINA® focuses exclusively on the growing specialty of vitreoretinal disorders. The Journal provides current information on diagnostic and therapeutic techniques. Its highly specialized and informative, peer-reviewed articles are easily applicable to clinical practice. In addition to regular reports from clinical and basic science investigators, RETINA® publishes special features including periodic review articles on pertinent topics, special articles dealing with surgical and other therapeutic techniques, and abstract cards. Issues are abundantly illustrated in vivid full color. Published 12 times per year, RETINA® is truly a “must have” publication for anyone connected to this field.