Adjuvant immunotherapy and targeted therapy in early and locally advanced resectable lung cancer: expanding treatment tentacles?

IF 2.3 Q2 RESPIRATORY SYSTEM Breathe Pub Date : 2024-08-27 eCollection Date: 2024-06-01 DOI:10.1183/20734735.0035-2024
Evaggelos Fergadis, Amadea Heitmann, Theodore Tsaras, Georgia Hardavella
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引用次数: 0

Abstract

Adjuvant platinum-based chemotherapy has been the main treatment following surgical resection with curative intent in early and locally advanced nonsmall cell lung cancer (NSCLC) albeit with a 5% improvement in 5-year survival rates. Recent advances in biomarkers pave the way for targeted treatments and immunotherapy in a broader spectrum of patients with subsequently improved clinical outcomes. Targeted treatments and immunotherapy have established their place in the adjuvant setting of resected NSCLC.

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早期和局部晚期可切除肺癌的辅助免疫疗法和靶向疗法:扩大治疗触角?
铂类辅助化疗一直是早期和局部晚期非小细胞肺癌(NSCLC)根治性手术切除后的主要治疗手段,尽管其 5 年生存率仅提高了 5%。生物标志物方面的最新进展为在更广泛的患者中开展靶向治疗和免疫疗法铺平了道路,从而改善了临床疗效。靶向治疗和免疫疗法已在切除的 NSCLC 的辅助治疗中占据了一席之地。
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来源期刊
Breathe
Breathe RESPIRATORY SYSTEM-
CiteScore
2.90
自引率
5.00%
发文量
51
审稿时长
12 weeks
期刊最新文献
An elderly woman with acute respiratory failure and diffuse pulmonary changes. Con: indwelling pleural catheters cause harm to patients. Erratum: "Steroids in severe community-acquired pneumonia". S. Ananth, A.G. Mathioudakis, J. Hansel. Breathe 2024; 20: 240081. Highlights from the Respiratory Failure and Mechanical Ventilation Conference 2024. Integration of lung function data: turning snapshots into stories.
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