Initial Misdiagnosis of Lung Cancer due to Elevated Carcinoembryonic Antigen in a Patient with Tuberculosis.

IF 0.7 4区 医学 Q4 MEDICAL LABORATORY TECHNOLOGY Clinical laboratory Pub Date : 2024-08-01 DOI:10.7754/Clin.Lab.2024.240242
Hong L Ji, Yan Wang, Jia F Luo, Cheng X Nie, Xin R Li, Yan L Ge, Ai S Fu
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Abstract

Background: Tuberculosis often presents on imaging in the form of a solitary nodule, sometimes accompanied by elevated CEA, which is clinically difficult to differentiate from lung cancer and prone to misdiagnosis.

Methods: Lung tissue taken by lung biopsy and sent for NGS and Xpert MTB/RIF finally led to the definitive diag-nosis of nodular foci in the upper lobe of the left lung caused by tuberculosis.

Results: Enhanced CT of the chest showed nodular foci in the upper lobe of the left lung. Initially the nodules were thought to be malignant, but after a series of tests, were finally confirmed to be tuberculosis.

Conclusions: In patients with lung disease, when chest imaging reveals a space-occupying lesion accompanied by an elevated CEA level, a comprehensive analysis of the type of lung disease, the patient's age, and comorbidities should be performed before final diagnosis to avoid misdiagnosis and delay in appropriate treatment.

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一名肺结核患者因癌胚抗原升高而被误诊为肺癌。
背景:肺结核在影像学上常表现为单发结节,有时伴有CEA升高,临床上很难与肺癌鉴别,容易误诊:方法:通过肺活检获取肺组织并送去做 NGS 和 Xpert MTB/RIF,最终明确诊断为结核引起的左肺上叶结节灶:胸部增强 CT 显示左肺上叶有结节灶。最初认为结节是恶性的,但经过一系列检查后,最终确诊为肺结核:结论:对于肺部疾病患者,当胸部影像学检查发现占位性病变并伴有 CEA 水平升高时,应在最终诊断前对肺部疾病类型、患者年龄和合并症进行综合分析,以避免误诊和延误适当的治疗。
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来源期刊
Clinical laboratory
Clinical laboratory 医学-医学实验技术
CiteScore
1.50
自引率
0.00%
发文量
494
审稿时长
3 months
期刊介绍: Clinical Laboratory is an international fully peer-reviewed journal covering all aspects of laboratory medicine and transfusion medicine. In addition to transfusion medicine topics Clinical Laboratory represents submissions concerning tissue transplantation and hematopoietic, cellular and gene therapies. The journal publishes original articles, review articles, posters, short reports, case studies and letters to the editor dealing with 1) the scientific background, implementation and diagnostic significance of laboratory methods employed in hospitals, blood banks and physicians'' offices and with 2) scientific, administrative and clinical aspects of transfusion medicine and 3) in addition to transfusion medicine topics Clinical Laboratory represents submissions concerning tissue transplantation and hematopoietic, cellular and gene therapies.
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