Importance of qSOFA Score in Terms of Prognosis and Mortality in Critical Care Patients.

IF 0.9 4区医学 Q4 MEDICINE, RESEARCH & EXPERIMENTAL Yonago acta medica Pub Date : 2024-08-27 eCollection Date: 2024-08-01 DOI:10.33160/yam.2024.08.009

Yahya Kemal Günaydın, Dilber Üçöz Kocaşaban, Sertaç Güler, Erdal Demirtaş, Yeşim Çövüt, Mitat Can Öztürk, Jiyan Deniz İlgün, Nazire Belgin Akıllı

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引用次数: 0

Abstract

Background: Recent studies have analyzed the qSOFA (quick sequential organ failure assessment) score as a prognostic indicator in many diseases, particularly sepsis. However, the effect of qSOFA score on prognosis and mortality in critical care patients has not been sufficiently analyzed. There is not enough data, especially regarding its use as critical care mortality and prognosis scoring. In this study, we aimed to analyze the effect of qSOFA score on mortality and prognosis in critical care unit (CCU) patients.

Methods: This study was conducted retrospectively using the chart review method. The APACHE II (Acute Physiology and Chronic Health Evaluation II) and SOFA (Sequential Organ Failure Assessment) scores of patients admitted to our CCU were compared with the qSOFA score. In addition, the need for intubation and mechanical ventilation, short- and long term mortality rates, the relationship between blood gas lactate values and qSOFA score were analyzed.

Results: A total of 1816 patients were included in the study. During critical care follow-up, 374 (20.6%) of our patients died, and at the end of 6 months, 796 (43.8%) of our patients died. A statistically significant association was found between in-hospital mortality and qSOFA, SOFA scores and lactate levels (P = 0.001, P = 0.001, P = 0.01 respectively). A statistically significant association was found between 6-month mortality and SOFA score only. (P = 0.001) The SOFA score appeared to be the most successful predictor of mortality. The cut-off for mortality using the ROC curve was ≥ 7 [sensitivity 78.1%; specificity 85.9%; AUC 0.91; 95% confidence interval (CI), 0.89 to 0.92; P = 0.001]. qSOFA scoring also performed well. The cut-off value for mortality using the ROC curve was ≥ 2 (sensitivity 42.5%; specificity 93.9%; AUC 0.83;95% CI, 0.80-0.85; P = 0.001).

Conclusion: We believe that the qSOFA score can be used as a marker for in-hospital mortality and prognosis in critical care patients. Especially in cases where the qSOFA score is ≥ 2, it provides valuable information regarding mortality and prognosis.

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qSOFA 评分对重症监护患者预后和死亡率的重要性。

背景：最近的研究分析了 qSOFA（快速序贯器官衰竭评估）评分作为许多疾病，尤其是败血症的预后指标。然而，qSOFA 评分对危重症患者预后和死亡率的影响尚未得到充分分析。特别是关于其作为重症监护死亡率和预后评分的使用，还没有足够的数据。本研究旨在分析 qSOFA 评分对重症监护病房（CCU）患者死亡率和预后的影响：本研究采用病历回顾法进行回顾性分析。方法：本研究采用病历回顾法对重症监护病房（CCU）患者的 APACHE II（急性生理学和慢性健康评估 II）和 SOFA（序贯器官衰竭评估）评分与 qSOFA 评分进行了比较。此外，还分析了插管和机械通气的需求、短期和长期死亡率、血气乳酸值与 qSOFA 评分之间的关系：研究共纳入了 1816 名患者。在重症监护随访期间，374 名患者（20.6%）死亡，6 个月后，796 名患者（43.8%）死亡。院内死亡率与 qSOFA、SOFA 评分和乳酸水平之间存在明显的统计学关联（分别为 P = 0.001、P = 0.001、P = 0.01）。仅在 6 个月死亡率与 SOFA 评分之间发现了具有统计学意义的关联（P = 0.001）。(P = 0.001) SOFA 评分似乎是最成功的死亡率预测指标。使用 ROC 曲线计算的死亡率临界值≥ 7 [灵敏度 78.1%；特异性 85.9%；AUC 0.91；95% 置信区间 (CI)，0.89 至 0.92；P = 0.001]。采用 ROC 曲线计算的死亡率临界值≥ 2（灵敏度 42.5%；特异性 93.9%；AUC 0.83；95% 置信区间 (CI)，0.80-0.85；P = 0.001）：我们认为，qSOFA 评分可作为危重症患者院内死亡率和预后的指标。结论：我们认为，qSOFA评分可作为重症监护患者院内死亡率和预后的指标，尤其是在qSOFA评分≥2分的情况下，它能为死亡率和预后提供有价值的信息。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Yonago acta medica MEDICINE, RESEARCH & EXPERIMENTAL-

CiteScore

1.60

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： Yonago Acta Medica (YAM) is an electronic journal specializing in medical sciences, published by Tottori University Medical Press, 86 Nishi-cho, Yonago 683-8503, Japan. The subject areas cover the following: molecular/cell biology; biochemistry; basic medicine; clinical medicine; veterinary medicine; clinical nutrition and food sciences; medical engineering; nursing sciences; laboratory medicine; clinical psychology; medical education. Basically, contributors are limited to members of Tottori University and Tottori University Hospital. Researchers outside the above-mentioned university community may also submit papers on the recommendation of a professor, an associate professor, or a junior associate professor at this university community. Articles are classified into four categories: review articles, original articles, patient reports, and short communications.