Preparation of Allium Cepa Peel Extract-mediated Silver Nanoparticles: A Hair Dye Formulation.

B Rama, Srujana K, K Sudhamani, Shweta Manoj Dhule, L Jyothi Rani, B Rajkamal, V Nagalaxmi
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Abstract

The burgeoning field of nanotechnology has ushered in innovative Novel drug delivery systems (NDDS) that enhance the efficacy, safety, and patient compliance of pharmaceutical treatments. This study explores the synthesis and application of silver nanoparticles (AgNPs) using green chemistry approaches, specifically leveraging plant extracts as reducing agents. AgNPs, known for their unique physical and chemical properties, including antimicrobial capabilities, offer significant potential in modern drug delivery. This study investigates the potential of using Allium cepa peel waste for the green synthesis of silver nanoparticles. This study also revealed the resultant formation of silver nanoparticles through microscopy and UV spectroscopy, which were further analyzed by Scanning Electron Microscopy. This green synthesis method not only aligns with environmentally friendly practices but also provides a cost-effective and scalable approach to nanoparticle production. We formulated a hair dye incorporating these AgNPs and evaluated its physicochemical parameters, demonstrating enhanced performance compared to control formulations without nanoparticles. This work underscores the promise of green-synthesized nanoparticles in developing advanced drug delivery systems, offering insights into future applications in anticancer and antimicrobial treatments. Our findings advocate for the broader adoption of sustainable nanotechnology in pharmaceutical sciences, potentially revolutionizing the treatment landscape with safer and more effective therapeutic options.

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制备薤白皮提取物介导的银纳米粒子:染发剂配方。
蓬勃发展的纳米技术领域带来了创新的新型给药系统(NDDS),可提高药物治疗的疗效、安全性和患者依从性。本研究采用绿色化学方法,特别是利用植物提取物作为还原剂,探索了银纳米粒子(AgNPs)的合成和应用。银纳米粒子以其独特的物理和化学特性(包括抗菌能力)而闻名,在现代药物输送方面具有巨大潜力。本研究探讨了利用薤白皮废弃物绿色合成银纳米粒子的潜力。本研究还通过显微镜和紫外光谱分析揭示了银纳米粒子的形成过程,并通过扫描电子显微镜对其进行了进一步分析。这种绿色合成方法不仅符合环保要求,而且提供了一种具有成本效益和可扩展的纳米粒子生产方法。我们配制了含有这些 AgNPs 的染发剂,并对其理化参数进行了评估,结果表明与不含纳米粒子的对照配方相比,染发剂的性能有所提高。这项工作强调了绿色合成纳米粒子在开发先进药物输送系统方面的前景,为未来在抗癌和抗菌治疗方面的应用提供了启示。我们的研究结果倡导在制药科学中更广泛地采用可持续纳米技术,从而有可能通过更安全、更有效的治疗方案彻底改变治疗格局。
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来源期刊
CiteScore
0.70
自引率
0.00%
发文量
53
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