[A Study on the Significance of NST Early Intervention for Cancer Patients].

Q4 Medicine Japanese Journal of Cancer and Chemotherapy Pub Date : 2024-07-01
Shonosuke Yasui, Takuya Hamakawa, Ayaka Kawabe, Mai Seki, Masakazu Miyagi, Masahiro Umezu, Atsushi Takeno, Kazuko Arakawa, Ayaka Wada, Midori Ishida, Ayako Otsuchi, Mayumi Yamamoto, Tsuyoshi Uchikawa, Yuko Naito, Hisashi Ishida, Motohiro Hirao
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Abstract

Background: Cancer patients are often complicated by weight loss and malnutrition, thus it is important to provide nutritional therapy in parallel with disease treatment. This study examined the significance of early intervention by NST for cancer patients.

Methods: Seventy-five cancer patients out of 281 patients who underwent NST intervention between July 2021 and June 2022 were included. Intervention outcomes, such as energy and protein sufficiency(=intake/target), and final evaluation by a NST nutritionist at the end of the intervention("improvement"/"unchanged"/"disease progression"/ "death"), were compared between patients who received NST intervention within 7 days from admission(Group A)and after 7 days from admission(Group B).

Results: Nutritional sufficiency at the end of NST intervention was higher in Group A for both energy and protein, and the proportion of"improvement"was higher in Group A for the final evaluation by a NST nutritionist. Patients' situation(pre-initial treatment/post-chemotherapy/post-surgery/worsening nutritional status during follow-up)was biased between 2 groups, however Group A showed better results for nutritional sufficiency rate and final evaluation in each subgroup of patients' situation.

Conclusion: Early intervention may improve the effectiveness of NST for cancer patients. It is important to extract subjects and start NST intervention at early timing.

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[癌症患者 NST 早期干预的意义研究]。
背景:癌症患者通常会出现体重下降和营养不良,因此在治疗疾病的同时提供营养治疗非常重要。本研究探讨了通过 NST 对癌症患者进行早期干预的意义:在 2021 年 7 月至 2022 年 6 月期间接受 NST 干预的 281 名癌症患者中,有 75 名患者被纳入研究。对入院 7 天内接受 NST 干预的患者(A 组)和入院 7 天后接受 NST 干预的患者(B 组)进行干预结果比较,如能量和蛋白质充足率(=摄入量/目标值)以及干预结束时 NST 营养师的最终评估("改善"/"不变"/"疾病进展"/"死亡"):结果:NST 干预结束时,A 组患者的能量和蛋白质营养充足率更高,NST 营养师最终评估的 "改善 "比例在 A 组更高。两组患者的情况(初始治疗前/化疗后/手术后/随访期间营养状况恶化)存在偏差,但在患者情况的各个分组中,A 组的营养充足率和最终评估结果均更好:结论:早期干预可提高癌症患者 NST 的效果。结论:早期干预可提高 NST 对癌症患者的疗效,因此必须尽早抽取受试者并开始 NST 干预。
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